SCHEMBL10122850

SCHEMBL10122850

c1ccc2c(c1)cc(-c1ccc3c(ccc4oc5ccc6cc(-c7cc8ccccc8c8ccccc78)ccc6c5c43)c1)c1ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.42
ABCG2 Q9UNQ0 4/20 0.42
AHR P35869 3/20 0.42
PAX8 Q06710 2/20 0.42
CYP1A2 P05177 2/20 0.42
FYN P06241 2/20 0.42
HPRT1 P00492 1/20 0.42
CYP1A1 P04798 1/20 0.42
MAPK3 P27361 1/20 0.42
TDP1 Q9NUW8 3/20 0.41
NPC1 O15118 2/20 0.41
GPR84 Q9NQS5 2/20 0.41
RAB9A P51151 1/20 0.41
ALDH1A1 P00352 2/20 0.41
HIF1A Q16665 2/20 0.41
HSD17B10 Q99714 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ERBB2 P04626 1/20 0.41
MAOA P21397 1/20 0.41
ACHE P22303 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9889854 0.88 CYP11B1 (0.44) CYP11B1ABCG2AHRPAX8CYP1A2
SCHEMBL12037331 0.86 GPR84 (0.42) CYP11B1HPRT1CYP1A1TDP1NPC1
SCHEMBL16417804 0.85 GPR84 (0.43) CYP11B1TDP1NPC1GPR84RAB9A
SCHEMBL12037041 0.85 GPR84 (0.43) CYP11B1AHRCYP1A2FYNHPRT1
SCHEMBL12037259 0.85 GPR84 (0.43) CYP11B1TDP1NPC1GPR84RAB9A
SCHEMBL13507248 0.85 ALDH1A1 (0.43) CYP11B1ABCG2AHRPAX8CYP1A2
SCHEMBL12037208 0.85 GPR84 (0.43) CYP11B1AHRCYP1A2FYNHPRT1
SCHEMBL22155156 0.85 ABCG2 (0.38) CYP11B1ABCG2AHRPAX8CYP1A2
SCHEMBL12037332 0.84 GPR84 (0.41) CYP11B1HPRT1CYP1A1TDP1NPC1
SCHEMBL12069425 0.84 CYP11B1 (0.46) CYP11B1AHRTDP1NPC1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9373792-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2016-06-21 US disclosed
US-9373792-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2016-06-21 US disclosed
US-20160141515-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-05-19 US disclosed
US-20160141515-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-05-19 US disclosed
EP-3010055-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME, AND ELECTRONIC DEVICE Idemitsu Kosan Co., Ltd (JP) 2016-04-20 EP disclosed
US-20150372237-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD (JP) 2015-12-24 US disclosed
US-20150372237-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD (JP) 2015-12-24 US disclosed
US-9147847-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2015-09-29 US disclosed
US-9147847-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2015-09-29 US disclosed
US-8946984-B2 Electroluminescent device BASF SE (DE) 2015-02-03 US disclosed
US-8629430-B2 Anthracene derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-01-14 US disclosed
US-20120138914-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
US-20120138914-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-06-07 US disclosed
US-20110248217-A1 ELECTROLUMINESCENT DEVICE UDC IRELAND LIMITED (IE) 2011-10-13 US disclosed
US-20110248217-A1 ELECTROLUMINESCENT DEVICE UDC IRELAND LIMITED (IE) 2011-10-13 US disclosed
US-7989644-B2 Electroluminescent device BASF SE (DE) 2011-08-02 US disclosed
US-7989644-B2 Electroluminescent device BASF SE (DE) 2011-08-02 US disclosed
EP-1885818-B1 ELECTROLUMINESCENT DEVICE BASF SE (DE) 2010-01-13 EP disclosed
US-20090131673-A1 Electroluminescent Device UDC IRELAND LIMITED (IE) 2009-05-21 US disclosed
US-20090131673-A1 Electroluminescent Device UDC IRELAND LIMITED (IE) 2009-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110248217-A1 ELECTROLUMINESCENT DEVICE DDT, CD99, EED CYP11B1 3764/4885ABCG2 1549/4885AHR 910/4885
US-20160141515-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME, AND ELECTRONIC DEVICE OR10J3, PIEZO1, L1CAM CYP11B1 4007/4885ABCG2 4690/4885AHR 4193/4885
US-20150372237-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME SOX18, ANXA1, ANXA11 CYP11B1 459/4885ABCG2 3770/4885AHR 314/4885
US-20120138914-A1 ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME SOX18, ANXA1, ANXA11 CYP11B1 459/4885ABCG2 3770/4885AHR 314/4885
US-20090131673-A1 Electroluminescent Device DDT, CD99, EED CYP11B1 3764/4885ABCG2 1549/4885AHR 910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.