SCHEMBL10123686

SCHEMBL10123686

C(=C/c1ccc(N(c2ccccc2)c2ccc3c(c2)c2cc(-c4cccc(-c5ccccc5)c4)ccc2n3-c2ccccc2)cc1)\c1ccc(N(c2ccccc2)c2ccc3c(c2)c2cc(-c4cccc(-c5ccccc5)c4)ccc2n3-c2ccccc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.34
ATM Q13315 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
KDM4E B2RXH2 2/20 0.34
TSPO P30536 1/20 0.33
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
CTNNB1 P35222 1/20 0.33
KMT2A Q03164 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CHEK1 O14757 2/20 0.32
RELA Q04206 1/20 0.32
CA1 P00915 1/20 0.31
MGLL Q99685 1/20 0.31
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10123625 0.99 RELA (0.34) APPATML3MBTL1KDM4ETSPO
SCHEMBL10123688 0.97 ATM (0.36) APPATML3MBTL1KDM4ETSPO
SCHEMBL10123684 0.97 ATM (0.36) APPATML3MBTL1KDM4ETSPO
SCHEMBL10123622 0.96 RELA (0.36) APPATML3MBTL1KDM4ETSPO
SCHEMBL10123624 0.96 RELA (0.36) APPATML3MBTL1KDM4ETSPO
SCHEMBL10123821 0.95 APP (0.36) APPATML3MBTL1KDM4ETSPO
SCHEMBL10123746 0.94 RELA (0.36) APPATML3MBTL1KDM4ETSPO
SCHEMBL10123814 0.92 APP (0.37) APPATML3MBTL1KDM4ETSPO
SCHEMBL10123812 0.92 APP (0.37) APPATML3MBTL1KDM4ETSPO
SCHEMBL10123653 0.92 L3MBTL1 (0.43) APPATML3MBTL1KDM4ETSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8901542-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-12-02 US disclosed
US-8901542-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-12-02 US disclosed
US-20120235130-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-09-20 US disclosed
US-20120235130-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-09-20 US disclosed
US-8193701-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-06-05 US disclosed
US-8193701-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-06-05 US disclosed
EP-1931634-B1 STILBENE DERIVATIVES, LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2011-11-09 EP disclosed
US-20110147729-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-06-23 US disclosed
US-20110147729-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-06-23 US disclosed
US-7898171-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-03-01 US disclosed
US-7898171-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-03-01 US disclosed
US-20090146558-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-06-11 US disclosed
US-7476745-B2 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-01-13 US disclosed
US-7476745-B2 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-01-13 US disclosed
WO-2007043371-A1 STILBENE DERIVATIVES, LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-04-19 WO disclosed
US-20070080630-A1 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-04-12 US disclosed
US-20070080630-A1 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090146558-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device NR0B1, NR2E3, NR0B2 APP 3044/4885ATM 1663/4885L3MBTL1 2135/4885
US-20070080630-A1 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability NR0B1, TERB1, CYP1B1 APP 4087/4885ATM 1342/4885L3MBTL1 1872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.