SCHEMBL10124680

SCHEMBL10124680

CCCON1C(C)(C)CC2(CC1(C)C)OC(=O)N(c1ccccc1)C2=O

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.38
PGR P06401 1/20 0.34
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CACNA1B Q00975 2/20 0.33
APBA1 Q02410 2/20 0.33
SLC6A2 P23975 2/20 0.32
HSD11B1 P28845 1/20 0.32
CTSG P08311 1/20 0.32
PRTN3 P24158 1/20 0.32
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10124682 0.91 ELANE (0.38) ELANEMAPTNPSR1ALDH1A1SLC6A2
SCHEMBL10124681 0.91 ELANE (0.38) ELANEMAPTNPSR1ALDH1A1SLC6A2
SCHEMBL10124677 0.90 ELANE (0.39) ELANEPGRALDH1A1CACNA1BAPBA1
SCHEMBL10124684 0.88 TRIP13 (0.36) CACNA1BAPBA1
SCHEMBL10124675 0.84 ELANE (0.36) ELANEPGRALDH1A1CACNA1BAPBA1
SCHEMBL18697264 0.81 ELANE (0.35) ELANEPGRALDH1A1CACNA1BAPBA1
SCHEMBL10124695 0.81 ELANE (0.33) ELANEMAPTNPSR1ALDH1A1CACNA1B
SCHEMBL10124653 0.78 ELANE (0.39) ELANEPGRMAPTNPSR1GAA
SCHEMBL10124678 0.78 CACNA1B (0.35) ELANEPGRNPSR1ALDH1A1CACNA1B
SCHEMBL10124697 0.73 GRM2 (0.35) ELANEMAPTNPSR1ALDH1A1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9045480-B2 Sterically hindered amine light stabilizers BASF SE (DE) 2015-06-02 US disclosed
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2012-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS AAAS, CRY1, TAAR1 ELANE 2936/4885PGR 2738/4885MAPT 276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.