SCHEMBL10124682

SCHEMBL10124682

CCCCCCCCCCCON1C(C)(C)CC2(CC1(C)C)OC(=O)N(c1ccccc1)C2=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.38
GRM2 Q14416 5/20 0.37
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
NPSR1 Q6W5P4 2/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
RECQL P46063 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GAA P10253 2/20 0.35
ALOX12 P18054 1/20 0.35
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
HTT P42858 2/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
SLC6A2 P23975 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10124681 1.00 ELANE (0.38) ELANEGRM2MEN1KMT2ANPSR1
SCHEMBL10124680 0.91 ELANE (0.38) ELANENPSR1GAAALDH1A1MAPT
SCHEMBL10124677 0.86 ELANE (0.39) ELANEGAAALDH1A1HPGDHSD17B10
SCHEMBL10124697 0.83 GRM2 (0.35) ELANEGRM2MEN1KMT2ANPSR1
SCHEMBL10124698 0.83 GRM2 (0.35) ELANEGRM2MEN1KMT2ANPSR1
SCHEMBL10124652 0.81 GAA (0.42) ELANEMEN1KMT2AGAAALOX12
SCHEMBL10124655 0.81 GAA (0.42) ELANEMEN1KMT2AGAAALOX12
SCHEMBL10124684 0.80 TRIP13 (0.36)
SCHEMBL10124675 0.80 ELANE (0.36) ELANEMEN1KMT2ACYP2C9CYP2C19
SCHEMBL10124689 0.78 PTGS1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9045480-B2 Sterically hindered amine light stabilizers BASF SE (DE) 2015-06-02 US disclosed
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2012-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS AAAS, CRY1, TAAR1 ELANE 2936/4885GRM2 3507/4885MEN1 1632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.