SCHEMBL10124668

SCHEMBL10124668

CCCCCCCCON1C(C)(C)CC2(CC1(C)C)C(=O)N(c1ccccc1)C(=O)N2Cc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.38
HTR1A P08908 2/20 0.35
HTR7 P34969 2/20 0.35
HTR6 P50406 2/20 0.35
TAS2R8 Q9NYW2 2/20 0.35
MCHR1 Q99705 4/20 0.35
NPSR1 Q6W5P4 1/20 0.34
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
ALOX12 P18054 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
GCGR P47871 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10124667 1.00 ELANE (0.38) ELANEHTR1AHTR7HTR6TAS2R8
SCHEMBL10124664 0.92 ELANE (0.40) ELANETAS2R8MCHR1NPSR1CYP1A2
SCHEMBL10124656 0.87 ELANE (0.41) ELANEHTR1AHTR7HTR6TAS2R8
SCHEMBL10124658 0.83 ELANE (0.41) ELANETAS2R8MCHR1NPSR1
SCHEMBL18697248 0.81 MCHR1 (0.41) ELANEHTR1AHTR7HTR6TAS2R8
SCHEMBL16769259 0.78 ELANE (0.43) ELANEHTR1AHTR7HTR6TAS2R8
SCHEMBL10124652 0.78 GAA (0.42) ELANEMEN1GAAALOX12KMT2A
SCHEMBL10124655 0.78 GAA (0.42) ELANEMEN1GAAALOX12KMT2A
SCHEMBL10124665 0.78 ELANE (0.36) ELANETAS2R8MCHR1MEN1KMT2A
SCHEMBL10124682 0.75 ELANE (0.38) ELANENPSR1MEN1GAAALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440557-B1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2017-04-05 EP disclosed
US-9045480-B2 Sterically hindered amine light stabilizers BASF SE (DE) 2015-06-02 US disclosed
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2012-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS AAAS, CRY1, TAAR1 ELANE 2936/4885HTR1A 274/4885HTR7 271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.