Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10126045 | 0.98 | ESR1 (0.46) | MTNR1AMTNR1BESR1ESR2TDP1 | |
| SCHEMBL10125874 | 0.93 | MTNR1A (0.43) | MTNR1AMTNR1BESR1ESR2TDP1 | |
| SCHEMBL10126048 | 0.86 | ESR1 (0.41) | MTNR1AMTNR1BESR1ESR2TDP1 | |
| SCHEMBL10125863 | 0.85 | DHODH (0.45) | MTNR1AMTNR1BESR1ESR2TDP1 | |
| SCHEMBL13621037 | 0.83 | MTNR1A (0.47) | MTNR1AMTNR1BESR1ESR2DHODH | |
| SCHEMBL10125878 | 0.81 | TDP1 (0.42) | MTNR1AMTNR1BTDP1DHODHMEN1 | |
| SCHEMBL10125889 | 0.79 | ESR1 (0.45) | MTNR1AMTNR1BESR1ESR2TDP1 | |
| SCHEMBL10126046 | 0.78 | TDP1 (0.38) | MTNR1AMTNR1BESR1ESR2TDP1 | |
| SCHEMBL10126051 | 0.76 | ESR1 (0.46) | MTNR1AMTNR1BESR1ESR2MEN1 | |
| SCHEMBL835217 | 0.76 | ESR1 (0.39) | MTNR1AMTNR1BESR1ESR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119259-B2 | Quinoxaline derivative, and light-emitting element and electronic device using the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20090140642-A1 | Quinoxaline Derivative, and Light-Emitting Element and Electronic Device Using the Same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090140642-A1 | Quinoxaline Derivative, and Light-Emitting Element and Electronic Device Using the Same | NDUFA11, NDUFA9, NDUFA12 | MTNR1A 658/4885MTNR1B 1389/4885ESR1 696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.