Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10128492 | 0.81 | MAPK1 (0.65) | MAPK1KDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL10840248 | 0.77 | MAPK1 (0.44) | MAPK1FAAHKDM4EALDH1A1MAPT | |
| SCHEMBL20518647 | 0.72 | CA1 (0.38) | MAPK1FAAHALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10128618 | 0.71 | PKM (0.38) | MAPK1FAAHKDM4EALDH1A1MAPT | |
| SCHEMBL18605657 | 0.65 | FAAH (0.41) | MAPK1FAAHKDM4EALDH1A1HDAC6 | |
| SCHEMBL11625488 | 0.65 | MTNR1A (0.37) | KDM4EALDH1A1MAPTHDAC6SMN1; SMN2 | |
| SCHEMBL5285726 | 0.64 | TP53 (0.59) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20517781 | 0.64 | KDM4E (0.37) | KDM4EALDH1A1HDAC6KMT2AFPR2 | |
| SCHEMBL13631407 | 0.63 | MAPK1 (0.72) | MAPK1KDM4EALDH1A1MAPTTRPV1 | |
| SCHEMBL14087509 | 0.63 | POLB (0.44) | FAAHKDM4EALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010186-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010186-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | SCD, SCD5, FASN | MAPK1 2271/4885FAAH 493/4885KDM4E 1727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.