Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769005 | 0.83 | ALDH1A1 (0.72) | ALDH1A1KDM4EPOLBATMNPSR1 | |
| Hydrochloric Acid SCHEMBL7405455 | 0.82 | ALDH1A1 (0.70) | ALDH1A1KDM4EPOLBATMNPSR1 | |
| SCHEMBL31669175 | 0.82 | ALDH1A1 (0.74) | ALDH1A1KDM4EPOLBATMNPSR1 | |
| SCHEMBL11619127 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KDM4EPOLBATMNPSR1 | |
| SCHEMBL30341017 | 0.79 | ALDH1A1 (0.69) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL13293671 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL10104480 | 0.78 | KDM4E (0.43) | ALDH1A1KDM4EPOLBATMNPSR1 | |
| SCHEMBL21400926 | 0.76 | KMT2A (0.53) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL10104533 | 0.76 | KDM4E (0.44) | ALDH1A1KDM4EPOLBATMNPSR1 | |
| SCHEMBL6735190 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4EPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106190-B2 | 2-aminobenzamide derivatives | ASTELLAS PHARMA INC. (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20090233900-A1 | 2-AMINOBENZAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233900-A1 | 2-AMINOBENZAMIDE DERIVATIVE | TRPV1, TRPV2, TRPV5 | ALDH1A1 1210/4885KDM4E 2205/4885POLB 4665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.