SCHEMBL10130478

SCHEMBL10130478

c1ccc(-c2c3ccccc3c(-c3cccc(-c4ccc(-c5cc6ccccc6c6c5oc5ccccc56)cc4)c3)c3ccccc23)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 2/20 0.41
PLA2G2A P14555 3/20 0.40
PLA2G4A P47712 3/20 0.40
KDM4E B2RXH2 3/20 0.38
RAB9A P51151 2/20 0.38
ALDH1A1 P00352 1/20 0.38
MAOB P27338 1/20 0.38
PLA2G10 O15496 1/20 0.38
CDC14B O60729 2/20 0.38
CDC14A Q9UNH5 2/20 0.38
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
ALOX5 P09917 2/20 0.36
RECQL P46063 1/20 0.36
ADORA2A P29274 3/20 0.35
ADORA3 P0DMS8 2/20 0.35
ADORA1 P30542 2/20 0.35
HSD17B1 P14061 1/20 0.35
HSD17B2 P37059 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10130465 0.96 ALOX5 (0.40) GPR84PLA2G2APLA2G4AKDM4ERAB9A
SCHEMBL10130475 0.94 GPR84 (0.40) GPR84PLA2G2APLA2G4AKDM4ERAB9A
SCHEMBL18996163 0.94 PLA2G2A (0.38) GPR84PLA2G2APLA2G4AKDM4ERAB9A
SCHEMBL10130456 0.94 PLA2G2A (0.38) GPR84PLA2G2APLA2G4AKDM4ERAB9A
SCHEMBL9950744 0.93 ALOX5 (0.39) GPR84KDM4ERAB9AALDH1A1MAOB
SCHEMBL9949996 0.93 KDM4E (0.43) GPR84PLA2G2APLA2G4AKDM4ERAB9A
SCHEMBL10130395 0.93 PLA2G2A (0.39) GPR84PLA2G2APLA2G4AKDM4ERAB9A
SCHEMBL10130405 0.93 PLA2G2A (0.39) GPR84PLA2G2APLA2G4AKDM4ERAB9A
SCHEMBL10130436 0.92 GPR84 (0.41) GPR84PLA2G2APLA2G4AKDM4ERAB9A
SCHEMBL9951354 0.92 GPR84 (0.41) GPR84PLA2G2APLA2G4AKDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-28 US disclosed
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material CYP1B1, CTNND1, CTNNB1 GPR84 3217/4885PLA2G2A 1889/4885PLA2G4A 2242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.