Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | BMPR1B | O00238 | 5/20 | 0.36 |
| ▸ | BMPR1A | P36894 | 5/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.36 |
| ▸ | ACVRL1 | P37023 | 5/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10132371 | 0.89 | DRD2 (0.48) | DRD3DRD2KCNH2ALDH1A1OPRM1 | |
| SCHEMBL10130975 | 0.84 | KCNH2 (0.46) | DRD3DRD2KCNH2BMPR1BBMPR1A | |
| SCHEMBL9950595 | 0.84 | KCNH2 (0.46) | DRD3DRD2KCNH2BMPR1BBMPR1A | |
| SCHEMBL10130965 | 0.84 | KCNH2 (0.46) | DRD3DRD2KCNH2BMPR1BBMPR1A | |
| SCHEMBL16281069 | 0.81 | BMPR1B (0.41) | DRD3DRD2KCNH2BMPR1BBMPR1A | |
| SCHEMBL10131034 | 0.81 | PRKDC (0.40) | KCNH2BMPR1BBMPR1ATGFBR1ACVRL1 | |
| SCHEMBL10131058 | 0.81 | BMPR1B (0.41) | DRD3DRD2KCNH2BMPR1BBMPR1A | |
| SCHEMBL10131066 | 0.81 | BMPR1B (0.41) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL2715051 | 0.81 | BMPR1B (0.41) | DRD3DRD2KCNH2BMPR1BBMPR1A | |
| SCHEMBL10131099 | 0.80 | SIGMAR1 (0.53) | ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906913-B2 | Azabicyclohexanes | PANACEA BIOTEC LIMITED (IN) | 2014-12-09 | — | — | US | disclosed |
| US-8906913-B2 | Azabicyclohexanes | PANACEA BIOTEC LIMITED (IN) | 2014-12-09 | — | — | US | disclosed |
| EP-2445887-B1 | NOVEL AZABICYCLOHEXANES | PANACEA BIOTEC LTD (IN) | 2014-11-05 | — | — | EP | disclosed |
| US-20120165320-A1 | NOVEL AZABICYCLOHEXANES | PANACEA BIOTEC LTD. (IN) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165320-A1 | NOVEL AZABICYCLOHEXANES | CYP3A43, UGT1A1, CYP3A4 | DRD3 594/4885DRD2 834/4885KCNH2 2683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.