Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.43 |
| ▸ | TUBB | P07437 | 7/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10132593 | 0.97 | ABCB1 (0.43) | IDO1EP300KAT8TUBB4ATUBB | |
| SCHEMBL10162994 | 0.89 | PDE1A (0.47) | IDO1EP300KAT8TUBB4ATUBB | |
| SCHEMBL10132632 | 0.88 | PARP1 (0.51) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10161814 | 0.87 | PARP1 (0.39) | IDO1EP300KAT8TUBB4ATUBB | |
| SCHEMBL12074162 | 0.85 | TDO2 (0.41) | IDO1EP300KAT8TUBB4ATUBB | |
| SCHEMBL10132782 | 0.85 | TUBB4A (0.46) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10132843 | 0.84 | POLB (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10132796 | 0.82 | TUBB4A (0.47) | IDO1EP300KAT8TUBB4ATUBB | |
| SCHEMBL10132753 | 0.81 | PDE3B (0.49) | IDO1EP300KAT8CTDSP1ALDH1A1 | |
| SCHEMBL10132809 | 0.80 | GAA (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
| WO-2010083436-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | CCNT1, XPO4, XDH | IDO1 1056/4885EP300 2319/4885KAT8 2510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.