Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 10/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 10/20 | 0.49 |
| ▸ | PDE1A | P54750 | 8/20 | 0.49 |
| ▸ | PDE1B | Q01064 | 8/20 | 0.49 |
| ▸ | PDE1C | Q14123 | 8/20 | 0.49 |
| ▸ | PDE5A | O76074 | 8/20 | 0.47 |
| ▸ | PDE4A | P27815 | 8/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10162994 | 0.88 | PDE1A (0.47) | PDE3BPDE3APDE1APDE1BPDE1C | |
| SCHEMBL10132601 | 0.81 | IDO1 (0.45) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL10132593 | 0.79 | ABCB1 (0.43) | KDM4ETSHRSMN1; SMN2ALDH1A1IDO1 | |
| SCHEMBL10132632 | 0.79 | PARP1 (0.51) | KDM4ELMNAALDH1A1IDO1 | |
| SCHEMBL10161814 | 0.77 | PARP1 (0.39) | PDE3BPDE3APDE1APDE1BPDE1C | |
| SCHEMBL10132796 | 0.75 | TUBB4A (0.47) | KDM4ELMNATSHRALDH1A1IDO1 | |
| SCHEMBL12074162 | 0.75 | TDO2 (0.41) | PDE3BPDE3APDE1APDE1BPDE1C | |
| SCHEMBL10132782 | 0.75 | TUBB4A (0.46) | KDM4ELMNAALDH1A1IDO1 | |
| SCHEMBL10132843 | 0.74 | POLB (0.48) | — | |
| SCHEMBL10132290 | 0.71 | PDE3B (0.44) | PDE3BPDE3APDE1APDE1BPDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | CCNT1, XPO4, XDH | PDE3B 2429/4885PDE3A 3139/4885PDE1A 4046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.