Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 3/20 | 0.39 |
| ▸ | EDNRB | P24530 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10132602 | 0.87 | NPSR1 (0.43) | EDNRAEDNRBALDH1A1LMNAHTT | |
| SCHEMBL10132591 | 0.85 | NPSR1 (0.42) | EDNRAEDNRBALDH1A1LMNAHTT | |
| SCHEMBL10132623 | 0.83 | ALDH1A1 (0.42) | EDNRAEDNRBALDH1A1LMNATARBP2 | |
| SCHEMBL10132636 | 0.82 | NPSR1 (0.42) | EDNRAEDNRBLMNATARBP2MAPT | |
| SCHEMBL10132869 | 0.81 | CYP19A1 (0.36) | EDNRAALDH1A1LMNAHTTHPGD | |
| SCHEMBL419335 | 0.78 | NPSR1 (0.38) | EDNRAEDNRBALDH1A1LMNAHTT | |
| Benzamide SCHEMBL424272 | 0.74 | NPSR1 (0.37) | EDNRAEDNRBHTTTARBP2HPGD | |
| SCHEMBL10163166 | 0.71 | TUBB4A (0.42) | ALDH1A1LMNAHTTHPGDMAPT | |
| SCHEMBL10163248 | 0.69 | TUBB4A (0.41) | ALDH1A1LMNAHTTMAPTTACR1 | |
| SCHEMBL10132696 | 0.69 | TUBB4A (0.41) | ALDH1A1LMNAHTTHPGDTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
| WO-2010083436-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | CCNT1, XPO4, XDH | EDNRA 1983/4885EDNRB 1588/4885ALDH1A1 3095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.