Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.40 |
| ▸ | TUBB | P07437 | 3/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24433 | 0.87 | CYP3A4 (0.56) | ACHECYP3A4MAPTTUBB1TUBB4A | |
| SCHEMBL11447 | 0.87 | ENPP2 (0.43) | ACHECYP3A4MAPTTUBB1TUBB4A | |
| SCHEMBL14721848 | 0.82 | CYP3A4 (0.50) | ACHECYP3A4MAPTTUBB1TUBB4A | |
| SCHEMBL3912855 | 0.82 | CYP3A4 (0.39) | ACHECYP3A4MAPTTUBB1TUBB4A | |
| SCHEMBL4671676 | 0.79 | ENPP2 (0.43) | ACHECYP3A4MAPTTUBB1TUBB4A | |
| SCHEMBL7435094 | 0.78 | CYP3A4 (0.42) | ACHECYP3A4MAPTTUBB1TUBB4A | |
| SCHEMBL10165239 | 0.78 | ENPP2 (0.36) | ACHETUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL16654430 | 0.78 | ALDH1A1 (0.47) | ACHECYP3A4MAPTTUBB1TUBB4A | |
| SCHEMBL29951539 | 0.78 | ENPP2 (0.38) | MAPTTUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL6337779 | 0.74 | HTR2A (0.51) | CYP3A4MAPTTUBB1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749363-A | A kind of preparation method of the methylphenylboronic acid pinacol ester of 3,4 dimethoxy 5 | 西北大学 | 2017-05-31 | — | — | CN | disclosed |
| US-8877772-B2 | Substituted pyrrolo[2,3-B]pyridines as MLK inhibitors | UNIVERSITY OF ROCHESTER (US) | 2014-11-04 | — | — | US | disclosed |
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
| WO-2007081966-A2 | SMALL MOLECULES FOR TREATING CANCER AND ABNORMAL CELL PROLIFERATION DISORDERS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | CCNT1, XPO4, XDH | ACHE 4187/4885CYP3A4 131/4885MAPT 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.