Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MYC | P01106 | 1/20 | 0.54 |
| ▸ | MAX | P61244 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12197689 | 0.91 | MAPT (0.53) | MAPTKDM4EMEN1KMT2AMYC | |
| SCHEMBL11009249 | 0.88 | MAPT (0.67) | MAPTKDM4EMEN1KMT2AMYC | |
| SCHEMBL15481298 | 0.85 | MAPT (0.56) | MAPTKDM4EMEN1KMT2AMYC | |
| SCHEMBL12412637 | 0.82 | ALDH1A1 (0.76) | MAPTKDM4EMEN1KMT2AGAA | |
| SCHEMBL12404443 | 0.81 | SMN1; SMN2 (0.71) | MAPTKDM4EMEN1KMT2AMYC | |
| SCHEMBL3497679 | 0.81 | MAPT (0.50) | MAPTKDM4EMEN1KMT2AMYC | |
| SCHEMBL10509816 | 0.81 | MAPT (0.47) | MAPTKDM4EMEN1KMT2AGAA | |
| SCHEMBL12412636 | 0.81 | L3MBTL1 (0.62) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL5438060 | 0.81 | IDO1 (0.70) | MAPTKDM4EMEN1KMT2AMYC | |
| SCHEMBL1754979 | 0.80 | MAPT (0.61) | MAPTKDM4EMEN1KMT2AMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210379561-A1 | OPTICAL SYSTEM FOR DISPLAYING THREE DIMENSIONAL IMAGE | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2021-12-09 | — | — | US | disclosed |
| US-9399652-B2 | Synthetic route to pactamycin and pactamycin analogs | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2016-07-26 | — | — | US | disclosed |
| US-20150329570-A1 | SYNTHETIC ROUTE TO PACTAMYCIN AND PACTAMYCIN ANALOGS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-11-19 | — | — | US | disclosed |
| WO-2015128272-A2 | PHOTO-SELECTIVE METHOD FOR BIOLOGICAL SAMPLE ANALYSIS FIELD | VENTANA MEDICAL SYSTEMS, INC. (US) | 2015-09-03 | — | — | WO | disclosed |
| US-8846320-B2 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | VENTANA MEDICAL SYSTEMS, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| WO-2012003476-A2 | HAPTEN CONJUGATES FOR TARGET DETECTION | VENTANA MEDICAL SYSTEMS, INC. (US) | 2012-01-05 | — | — | WO | disclosed |
| US-8084641-B2 | Organocataslysts and methods of use in chemical synthesis | STC.UNM (US) | 2011-12-27 | — | — | US | disclosed |
| US-20100184087-A1 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | VENTANA MEDICAL SYSTEMS, INC. | 2010-07-22 | — | — | US | disclosed |
| US-20090088588-A1 | Organocatalysts and methods of use in chemical synthesis | REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2009-04-02 | — | — | US | disclosed |
| US-4173645-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-11-06 | — | — | US | disclosed |
| US-4148799-A | Process for the preparation of 2-aryliminothiazoline solutions | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329570-A1 | SYNTHETIC ROUTE TO PACTAMYCIN AND PACTAMYCIN ANALOGS | PAICS, DPM1, MANBA | MAPT 1818/4885KDM4E 3235/4885MEN1 82/4885 |
| US-20090088588-A1 | Organocatalysts and methods of use in chemical synthesis | ICMT, PPOX, CYP4F3 | MAPT 2645/4885KDM4E 2323/4885MEN1 556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.