SCHEMBL10133792

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15469118	0.86	TOP2A (0.43)	UGT2B7ALDH1A1MEN1CYP1A2CYP2D6
	SCHEMBL2491242	0.82	UGT2B7 (0.52)	UGT2B7ALDH1A1USP2GAAPKM
	SCHEMBL5401290	0.81	UGT2B7 (0.59)	UGT2B7ALDH1A1USP2GAAPKM
	SCHEMBL16684715	0.81	UGT2B7 (0.59)	UGT2B7ALDH1A1USP2GAAPKM
	SCHEMBL9968161	0.77	ALDH1A1 (0.44)	ALDH1A1USP2GAAPKMHPGD
	SCHEMBL12083593	0.77	GPR3 (0.52)	ALDH1A1USP2GAAPKMHPGD
	SCHEMBL18700709	0.77	ALDH1A1 (0.47)	ALDH1A1GAAPKMHPGDALOX15
	SCHEMBL3727201	0.77	ALDH1A1 (0.50)	UGT2B7ALDH1A1USP2GAAPKM
	SCHEMBL3725681	0.77	ALDH1A1 (0.50)	UGT2B7ALDH1A1USP2GAAPKM
	SCHEMBL9167387	0.77	ALDH1A1 (0.53)	UGT2B7ALDH1A1USP2GAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.