SCHEMBL10133974

SCHEMBL10133974

C=C1N(c2ccccc2)CCN1c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.58
NPC1 O15118 2/20 0.58
RAB9A P51151 2/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
DDB1 Q16531 1/20 0.42
CRBN Q96SW2 1/20 0.42
LMNA P02545 2/20 0.39
HTR3E A5X5Y0 1/20 0.39
HTR3B O95264 1/20 0.39
ADRB1 P08588 1/20 0.39
HTR3A P46098 1/20 0.39
HTR3D Q70Z44 1/20 0.39
HTR3C Q8WXA8 1/20 0.39
DRD2 P14416 1/20 0.38
DRD3 P35462 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9668729 0.78 SIGMAR1 (0.64) SIGMAR1NPC1RAB9AMEN1KMT2A
SCHEMBL3257577 0.74 SIGMAR1 (0.58) SIGMAR1NPC1RAB9AMEN1KMT2A
SCHEMBL610584 0.74 NPC1 (1.00) SIGMAR1NPC1RAB9AMEN1KMT2A
SCHEMBL11174174 0.74 SIGMAR1 (1.00) SIGMAR1NPC1RAB9AMEN1KMT2A
SCHEMBL17704774 0.74 NPC1 (0.73) SIGMAR1NPC1RAB9AMEN1KMT2A
SCHEMBL2452595 0.74 SIGMAR1 (0.58) SIGMAR1NPC1RAB9AMEN1KMT2A
SCHEMBL17956811 0.74 SIGMAR1 (0.58) SIGMAR1NPC1RAB9AMEN1KMT2A
SCHEMBL21507867 0.72 SIGMAR1 (0.45) SIGMAR1NPC1RAB9AMEN1KMT2A
SCHEMBL14223264 0.70 SIGMAR1 (0.43) SIGMAR1NPC1RAB9AMEN1KMT2A
SCHEMBL7448866 0.70 NPC1 (0.72) SIGMAR1NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2439803-B1 PHOTOELECTRIC CONVERSION ELEMENT AND METHOD FOR PRODUCING SAME, PHOTOSENSOR, IMAGING ELEMENT AND METHOD OF DRIVING SAME FUJIFILM CORP (JP) 2017-11-08 EP disclosed
US-9349965-B2 Photoelectric conversion material, film containing the material, photoelectric conversion device, method for preparing photoelectric conversion device, method for using photoelectric conversion device, photosensor and imaging device FUJIFILM CORPORATION (JP) 2016-05-24 US disclosed
US-9349965-B2 Photoelectric conversion material, film containing the material, photoelectric conversion device, method for preparing photoelectric conversion device, method for using photoelectric conversion device, photosensor and imaging device FUJIFILM CORPORATION (JP) 2016-05-24 US disclosed
US-20150129861-A1 ORGANIC MATERIAL FOR DEPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, DEPOSITION METHOD, AND MANUFACTURING METHOD FOR ORGANIC PHOTOELECTRONIC ONVERSION ELEMENT OBTAINED USING THE SAME FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-20150129861-A1 ORGANIC MATERIAL FOR DEPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, DEPOSITION METHOD, AND MANUFACTURING METHOD FOR ORGANIC PHOTOELECTRONIC ONVERSION ELEMENT OBTAINED USING THE SAME FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-9012762-B2 Photoelectric conversion element and imaging device FUJIFILM CORPORATION (JP) 2015-04-21 US disclosed
US-9012762-B2 Photoelectric conversion element and imaging device FUJIFILM CORPORATION (JP) 2015-04-21 US disclosed
US-20140374733-A1 PHOTOELECTRIC CONVERSION ELEMENT, METHOD FOR USING THE SAME, IMAGING DEVICE, PHOTOSENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2014-12-25 US disclosed
US-20140374733-A1 PHOTOELECTRIC CONVERSION ELEMENT, METHOD FOR USING THE SAME, IMAGING DEVICE, PHOTOSENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2014-12-25 US disclosed
EP-2786983-A1 Compounds for use in a photoelectric conversion material, and intermediates for the preparation thereof Fujifilm Corporation (JP) 2014-10-08 EP disclosed
US-20110063485-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS FUJIFILM CORPORATION (JP) 2011-03-17 US disclosed
US-20110063485-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS FUJIFILM CORPORATION (JP) 2011-03-17 US disclosed
EP-2292586-A2 Photoelectric conversion material, film containing the material, photoelectric conversion device, production method thereof, photosensor, imaging device and their use methods Fujifilm Corporation (JP) 2011-03-09 EP disclosed
US-20100308312-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100308312-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100308372-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100308372-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
EP-2259359-A2 Photoelectric conversion device, production method thereof and imaging device Fujifilm Corporation (JP) 2010-12-08 EP disclosed
US-20090223566-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2009-09-10 US disclosed
US-20090223566-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2009-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110063485-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS PPOX, CRY1, FTO SIGMAR1 4866/4885NPC1 3333/4885RAB9A 997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.