Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | PDE5A | O76074 | 3/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5213000 | 0.85 | GABRA5 (0.53) | SMN1; SMN2KMT2AALDH1A1MAPTGAA | |
| Hydrochloric Acid SCHEMBL6152648 | 0.84 | GABRA5 (0.51) | SMN1; SMN2KMT2AALDH1A1MAPTGAA | |
| SCHEMBL11143253 | 0.84 | KMT2A (0.40) | SMN1; SMN2KMT2AALDH1A1MAPTGAA | |
| SCHEMBL11143259 | 0.84 | CSNK2A1 (0.46) | SMN1; SMN2KMT2AALDH1A1MAPTGAA | |
| SCHEMBL10134063 | 0.81 | ALDH1A1 (0.58) | SMN1; SMN2KMT2AALDH1A1MAPTGAA | |
| SCHEMBL9050304 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2KMT2AALDH1A1MAPTGAA | |
| SCHEMBL676084 | 0.78 | SMN1; SMN2 (0.64) | SMN1; SMN2KMT2AALDH1A1MAPTGAA | |
| SCHEMBL2448139 | 0.77 | SCD (0.39) | SMN1; SMN2KMT2AALDH1A1MAPTPOLB | |
| Hydrochloric Acid SCHEMBL9329409 | 0.76 | SMN1; SMN2 (0.69) | SMN1; SMN2KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL9686219 | 0.76 | KMT2A (0.53) | SMN1; SMN2KMT2AALDH1A1GAAPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016024284-A2 | A PROCESS FOR THE PREPARATION OF MIRABEGRON AND ITS INTERMEDIATES | WANBURY LTD. (IN) | 2016-02-18 | — | — | WO | disclosed |
| EP-1278754-B1 | CEPHALOSPORIN INTERMEDIATES | SANDOZ AG (CH) | 2005-01-26 | — | — | EP | disclosed |
| US-6787649-B2 | Cephalosporin intermediates | SANDOZ GMBH (AT) | 2004-09-07 | — | — | US | disclosed |
| US-20030153748-A1 | Cephalosporin intermediates | SANDOZ GMBH (FORMERLY BIOCHEMIE GMBH) (AU) | 2003-08-14 | — | — | US | disclosed |
| EP-1278754-A1 | CEPHALOSPORIN INTERMEDIATES | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2003-01-29 | — | — | EP | disclosed |
| WO-2001083491-A1 | CEPHALOSPORIN INTERMEDIATES | BIOCHEMIE GESELLSCHAFT M B H (AT) | 2001-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153748-A1 | Cephalosporin intermediates | MRPL21, MGAM, BLVRB | SMN1; SMN2 4631/4885KMT2A 3987/4885ALDH1A1 2884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.