SCHEMBL10134172

SCHEMBL10134172

O=C1C(=Cc2ccc(N(c3ccc(-c4cccs4)s3)c3ccc(-c4cccs4)s3)cc2)C(=O)c2cc3ccccc3cc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.38
EGFR P00533 1/20 0.37
RET P07949 1/20 0.37
KDR P35968 1/20 0.37
CTRC Q99895 1/20 0.37
KMT2A Q03164 6/20 0.36
HPGD P15428 4/20 0.36
ALDH1A1 P00352 4/20 0.36
HTT P42858 1/20 0.36
MAPT P10636 5/20 0.34
MEN1 O00255 4/20 0.34
POLB P06746 3/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
PKM P14618 3/20 0.34
THRB P10828 2/20 0.34
MAPK1 P28482 2/20 0.34
MDM2 Q00987 2/20 0.34
GAA P10253 1/20 0.34
TNNI3 P19429 1/20 0.34
TNNT2 P45379 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10134180 0.97 MAOB (0.36) MAOBEGFRRETKDRCTRC
SCHEMBL10134162 0.91 ALDH1A1 (0.45) EGFRRETKDRCTRCKMT2A
SCHEMBL10134163 0.88 ALDH1A1 (0.42) EGFRRETKDRCTRCKMT2A
SCHEMBL10134171 0.85 KMT2A (0.41) KMT2AHPGDALDH1A1HTTMAPT
SCHEMBL10134179 0.81 KMT2A (0.40) KMT2AHPGDALDH1A1HTTMAPT
SCHEMBL2606262 0.76 MAPT (0.47) KMT2AHPGDALDH1A1MAPTMEN1
SCHEMBL10134160 0.75 KMT2A (0.53) KMT2AHPGDALDH1A1HTTMAPT
SCHEMBL12761454 0.74 APP (0.38) KMT2AHPGDALDH1A1MAPTMEN1
SCHEMBL10134189 0.74 TNFRSF1A (0.45) EGFRRETKDRCTRCKMT2A
SCHEMBL12793944 0.74 MAPT (0.41) KMT2AHPGDALDH1A1HTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9349965-B2 Photoelectric conversion material, film containing the material, photoelectric conversion device, method for preparing photoelectric conversion device, method for using photoelectric conversion device, photosensor and imaging device FUJIFILM CORPORATION (JP) 2016-05-24 US disclosed
US-9349965-B2 Photoelectric conversion material, film containing the material, photoelectric conversion device, method for preparing photoelectric conversion device, method for using photoelectric conversion device, photosensor and imaging device FUJIFILM CORPORATION (JP) 2016-05-24 US disclosed
US-20150129861-A1 ORGANIC MATERIAL FOR DEPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, DEPOSITION METHOD, AND MANUFACTURING METHOD FOR ORGANIC PHOTOELECTRONIC ONVERSION ELEMENT OBTAINED USING THE SAME FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-20150129861-A1 ORGANIC MATERIAL FOR DEPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, DEPOSITION METHOD, AND MANUFACTURING METHOD FOR ORGANIC PHOTOELECTRONIC ONVERSION ELEMENT OBTAINED USING THE SAME FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-9012762-B2 Photoelectric conversion element and imaging device FUJIFILM CORPORATION (JP) 2015-04-21 US disclosed
US-9012762-B2 Photoelectric conversion element and imaging device FUJIFILM CORPORATION (JP) 2015-04-21 US disclosed
US-8847141-B2 Photoelectric conversion element, production method thereof, photosensor, imaging device and their driving method FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-8847208-B2 Photoelectric conversion device and imaging device having decreased dark current FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-8847208-B2 Photoelectric conversion device and imaging device having decreased dark current FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-8847141-B2 Photoelectric conversion element, production method thereof, photosensor, imaging device and their driving method FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-8378339-B2 Photoelectric conversion device, production method thereof, photosensor, imaging device and their drive methods FUJIFILM CORPORATION (JP) 2013-02-19 US disclosed
US-8338691-B2 Photoelectric conversion element and imaging device FUJIFILM CORPORATION (JP) 2012-12-25 US disclosed
US-8258506-B2 Photoelectric conversion device, production method thereof and imaging device FUJIFILM CORPORATION (JP) 2012-09-04 US disclosed
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD FUJIFILM CORPORATION (JP) 2012-04-05 US disclosed
EP-2306541-A1 Photoelectric conversion device, production method thereof, photosensor, imaging device and their drive methods Fujifilm Corporation (JP) 2011-04-06 EP disclosed
US-20110063485-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS FUJIFILM CORPORATION (JP) 2011-03-17 US disclosed
US-20100308311-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100308312-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100308372-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20090223566-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2009-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD SUN2, CYBA, PPOX MAOB 1058/4885EGFR 3029/4885RET 2328/4885
US-20110063485-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS PPOX, CRY1, FTO MAOB 724/4885EGFR 3985/4885RET 1535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.