SCHEMBL10136273

SCHEMBL10136273

c1ccc(Nc2ccc(-c3ccc(-c4ccccc4)cc3)c3ccccc23)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.61
KMT2A Q03164 5/20 0.61
GAA P10253 4/20 0.61
TDP1 Q9NUW8 4/20 0.61
KDM4E B2RXH2 3/20 0.61
MAPT P10636 3/20 0.61
GLA P06280 2/20 0.61
RECQL P46063 1/20 0.61
ALDH1A1 P00352 6/20 0.50
HPGD P15428 3/20 0.50
HSD17B10 Q99714 3/20 0.50
CDC25B P30305 3/20 0.50
ALOX15 P16050 3/20 0.50
ATM Q13315 2/20 0.50
TSHR P16473 2/20 0.50
CYP3A4 P08684 2/20 0.50
TP53 P04637 1/20 0.50
ALK Q9UM73 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.46
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30724554 1.00 MEN1 (0.61) MEN1KMT2AGAATDP1KDM4E
SCHEMBL30035801 0.96 MEN1 (0.55) MEN1KMT2AGAATDP1KDM4E
SCHEMBL21905514 0.96 MEN1 (0.55) MEN1KMT2AGAATDP1KDM4E
SCHEMBL29892449 0.96 MEN1 (0.55) MEN1KMT2AGAATDP1KDM4E
SCHEMBL13979466 0.96 MEN1 (0.55) MEN1KMT2AGAATDP1KDM4E
SCHEMBL1899884 0.96 MEN1 (0.55) MEN1KMT2AGAATDP1KDM4E
SCHEMBL30967405 0.96 MEN1 (0.65) MEN1KMT2AGAATDP1KDM4E
SCHEMBL1898742 0.96 MEN1 (0.65) MEN1KMT2AGAATDP1KDM4E
SCHEMBL12193251 0.94 TDP1 (0.53) MEN1KMT2AGAATDP1KDM4E
SCHEMBL15906450 0.94 TDP1 (0.53) MEN1KMT2AGAATDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117715890-A Compound and organic light emitting device comprising the same 株式会社LG化学 2024-03-15 CN disclosed
WO-2023027328-A1 COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2023-03-02 WO disclosed
US-8883324-B2 Aromatic amine derivative and organic electroluminescent device using same IDEMITSU KOSAN CO., LTD. (JP) 2014-11-11 US disclosed
US-8883324-B2 Aromatic amine derivative and organic electroluminescent device using same IDEMITSU KOSAN CO., LTD. (JP) 2014-11-11 US disclosed
US-20120302793-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. 2012-11-29 US disclosed
US-20120302793-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. 2012-11-29 US disclosed
US-20120228594-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-09-13 US disclosed
US-20120228594-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-09-13 US disclosed
US-20120184776-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 US disclosed
US-20120184776-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 US disclosed
US-20120112176-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed
US-20120112176-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed
US-20080303417-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same IDEMITSU KOSAN CO., LTD. (JP) 2008-12-11 US disclosed
US-20080303417-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same IDEMITSU KOSAN CO., LTD. (JP) 2008-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120184776-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME EML4, DDC, ALKBH2 MEN1 2329/4885KMT2A 241/4885GAA 2572/4885
US-20120302793-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME NAT1, AFF1, AOC2 MEN1 1440/4885KMT2A 299/4885GAA 4052/4885
US-20120112176-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME EML4, DDC, ALKBH2 MEN1 2291/4885KMT2A 232/4885GAA 2556/4885
US-20080303417-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same DDC, AOC2, ALKBH2 MEN1 2347/4885KMT2A 180/4885GAA 2609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.