Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 11/20 | 0.61 |
| ▸ | KIF11 | P52732 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 5/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.57 |
| ▸ | DRD2 | P14416 | 5/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.57 |
| ▸ | HTR2A | P28223 | 5/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.57 |
| ▸ | HRH1 | P35367 | 5/20 | 0.57 |
| ▸ | DRD3 | P35462 | 5/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10136874 | 0.90 | KDM1A (0.64) | KDM1AHTR1AADRA2ADRD2ADRA2C | |
| SCHEMBL2615404 | 0.85 | KDM1A (0.80) | KDM1AHTR1AADRA2ADRD2ADRA2C | |
| SCHEMBL10136856 | 0.85 | DRD2 (0.56) | KDM1AKIF11HTR1AADRA2ADRD2 | |
| SCHEMBL10168751 | 0.85 | KIF11 (0.80) | KIF11HTR1AADRA2ADRD2ADRA2C | |
| SCHEMBL26002746 | 0.84 | KDM1A (0.81) | KDM1AHTR1AADRA2ADRD2ADRA2C | |
| SCHEMBL25513974 | 0.84 | KDM1A (0.68) | KDM1AHTR1AADRA2ADRD2ADRA2C | |
| SCHEMBL10136857 | 0.83 | KDM1A (0.61) | KDM1AKIF11HTR1AADRA2ADRD2 | |
| SCHEMBL2615383 | 0.83 | LMNA (0.75) | KDM1AHTR1AADRA2ADRD2ADRA2C | |
| SCHEMBL10136955 | 0.82 | DRD2 (0.55) | KDM1AKIF11HTR1AADRA2ADRD2 | |
| SCHEMBL10136880 | 0.82 | KDM1A (0.54) | KDM1AKIF11HTR1AADRA2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035161-A1 | Novel Compositions and Methods of Treating Diseases Using the Same | CORRIDOR PHARMACEUTICALS, INC. | 2012-02-09 | — | — | US | disclosed |
| US-7923445-B2 | 10-{3-[4-(2-Amino)ethylpiperazinyl]propyl}2-trifluoromethylphenothiazine and analogues and derivatives; antiproliferative agents; serotonin receptor antagonists; apoptosis in activated lymphocytes, including T, B, and and mylenoma cells; asthma; antiarthritic agents; rheumatic diseeases | IMMUNE CONTROL, INC. (US) | 2011-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035161-A1 | Novel Compositions and Methods of Treating Diseases Using the Same | NFATC1, BAX, BCL2 | KDM1A 1810/4885KIF11 3636/4885HTR1A 3332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.