Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.80 |
| ▸ | MAPT | P10636 | 6/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.76 |
| ▸ | HTR1A | P08908 | 6/20 | 0.76 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.76 |
| ▸ | DRD2 | P14416 | 6/20 | 0.76 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.76 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.76 |
| ▸ | HTR2A | P28223 | 6/20 | 0.76 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.76 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.76 |
| ▸ | HRH1 | P35367 | 6/20 | 0.76 |
| ▸ | DRD3 | P35462 | 6/20 | 0.76 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.76 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.76 |
| ▸ | LMNA | P02545 | 6/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.76 |
| ▸ | DRD1 | P21728 | 5/20 | 0.76 |
| ▸ | TP53 | P04637 | 5/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13400183 | 0.93 | KDM1A (0.69) | KDM1AMAPTMAPK1HTR1AADRA2A | |
| SCHEMBL25513974 | 0.91 | KDM1A (0.68) | KDM1AMAPTMAPK1HTR1AADRA2A | |
| SCHEMBL26002746 | 0.91 | KDM1A (0.81) | KDM1AMAPTMAPK1HTR1AADRA2A | |
| SCHEMBL10136874 | 0.90 | KDM1A (0.64) | KDM1AMAPTMAPK1HTR1AADRA2A | |
| SCHEMBL2615383 | 0.90 | LMNA (0.75) | KDM1AMAPTMAPK1HTR1AADRA2A | |
| Perazine SCHEMBL29390464 | 0.89 | KDM1A (1.00) | KDM1AMAPTMAPK1HTR1AADRA2A | |
| Perazine SCHEMBL147165 | 0.89 | KDM1A (1.00) | KDM1AMAPTMAPK1HTR1AADRA2A | |
| SCHEMBL20425955 | 0.88 | KDM1A (0.65) | KDM1AMAPTMAPK1HTR1AADRA2A | |
| SCHEMBL20425951 | 0.88 | KDM1A (0.62) | KDM1AMAPTMAPK1HTR1AADRA2A | |
| SCHEMBL10136870 | 0.88 | KDM1A (0.62) | KDM1AMAPTMAPK1HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170105999-A1 | METHOD FOR TREATING DRUG RESISTANT CANCER | NAT YANG MING UNIV (TW) | 2017-04-20 | — | — | US | disclosed |
| US-20140350081-A1 | INSECT G-COUPLED RECEPTORS USEFUL AS TARGETS FOR INSECTICIDES AND COMPOUNDS AND REAGENTS IDENTIFIED USING THE SAME | US ARMY, SECRETARY OF THE ARMY | 2014-11-27 | — | — | US | disclosed |
| US-20140350081-A1 | INSECT G-COUPLED RECEPTORS USEFUL AS TARGETS FOR INSECTICIDES AND COMPOUNDS AND REAGENTS IDENTIFIED USING THE SAME | US ARMY, SECRETARY OF THE ARMY | 2014-11-27 | — | — | US | disclosed |
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2012-04-19 | — | — | US | disclosed |
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350081-A1 | INSECT G-COUPLED RECEPTORS USEFUL AS TARGETS FOR INSECTICIDES AND COMPOUNDS AND REAGENTS IDENTIFIED USING THE SAME | DDT, ADRA2C, MCHR1 | KDM1A 3543/4885MAPT 1678/4885MAPK1 1063/4885 |
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | FLI1, CDC73, FOS | KDM1A 2949/4885MAPT 3107/4885MAPK1 4320/4885 |
| US-20170105999-A1 | METHOD FOR TREATING DRUG RESISTANT CANCER | SLC11A2, ABCC1, FOLH1 | KDM1A 2792/4885MAPT 4426/4885MAPK1 3790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.