SCHEMBL101381

SCHEMBL101381

CC(S)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHCY P23526 9/20 0.63
ADORA2B P29275 3/20 0.63
ADORA3 P0DMS8 2/20 0.63
DOT1L Q8TEK3 2/20 0.63
ADORA2A P29274 2/20 0.63
DPP4 P27487 1/20 0.63
MEN1 O00255 1/20 0.63
SLC28A1 O00337 1/20 0.63
MAP3K7 O43318 1/20 0.63
SLC28A2 O43868 1/20 0.63
GAPDH P04406 1/20 0.63
MAPK1 P28482 1/20 0.63
ADORA1 P30542 1/20 0.63
STAT6 P42226 1/20 0.63
PI4KA P42356 1/20 0.63
KMT2A Q03164 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
PI4K2B Q8TCG2 1/20 0.63
SLC29A1 Q99808 1/20 0.63
PI4K2A Q9BTU6 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29352139 1.00 AHCY (0.63) AHCYADORA2BADORA3DOT1LADORA2A
SCHEMBL800346 0.90 PRMT5 (0.64) AHCYADORA2BADORA3DOT1LADORA2A
SCHEMBL22326785 0.90 PRMT5 (0.64) AHCYADORA2BADORA3DOT1LADORA2A
SCHEMBL800381 0.90 PRMT5 (0.64) AHCYADORA2BADORA3DOT1LADORA2A
SCHEMBL18520788 0.90 PRMT5 (0.64) AHCYADORA2BADORA3DOT1LADORA2A
SCHEMBL16300875 0.90 PRMT5 (0.64) AHCYADORA2BADORA3DOT1LADORA2A
SCHEMBL21413837 0.90 PRMT5 (0.64) AHCYADORA2BADORA3DOT1LADORA2A
SCHEMBL22326787 0.90 PRMT5 (0.64) AHCYADORA2BADORA3DOT1LADORA2A
SCHEMBL13173634 0.90 PRMT5 (0.64) AHCYADORA2BADORA3DOT1LADORA2A
SCHEMBL13134675 0.90 PRMT5 (0.64) AHCYADORA2BADORA3DOT1LADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 812 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144829-A1 SYNBIOTIC COMPOSITION, METABOLITES, AND METHOD OF PREVENTING AND TREATING OBESITY-RELATED DISEASE Hsu, Cheng-Chih (TW) 2026-05-28 US claimed
US-20260051387-A1 METABOLOMIC ANALYSIS OF PERITONEAL DIALYSIS EFFLUENT FRESENIUS MEDICAL CARE HOLDINGS, INC. (US) 2026-02-19 US claimed
US-20250341515-A1 METABOLOMIC BIOMARKERS FOR ACUTE KIDNEY INJURY, ASSAYS, COMPOSITIONS AND METHODS OF USE THEREOF WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2025-11-06 US claimed
EP-4597111-A1 USE OF METABOLIC MARKER FOR DIAGNOSIS OF LUNG CANCER STAGING AND KIT Harbin Metanotitia Inc. (CN) 2025-08-06 EP claimed
WO-2025085615-A1 METHODS TO RAPIDLY DETECT METHYLTHIOADENOSINE AND RELATED METABOLITES DIRECTLY FROM PATIENT SAMPLES TO IDENTIFY 9P21 LOSS CANCERS AND TREATMENT STRATEGIES FOR PATIENTS BAYLOR COLLEGE OF MEDICINE (US) 2025-04-24 WO claimed
US-20240385183-A1 METABOLIC AND MICROBIAL BIOMARKERS FOR DETECTION OF PANCREATICOBILIARY CANCERS NORTHWESTERN UNIVERSITY 2024-11-21 US claimed
WO-2024230650-A1 SYNBIOTIC COMPOSITION, METABOLITE AND USE THEREOF IN PREVENTION AND TREATMENT OF OBESITY-RELATED DISEASES 徐丞志 2024-11-14 WO claimed
WO-2024152730-A1 BIOMARKERS FOR IDENTIFYING INFREQUENT GOUT FLARES AND FREQUENT GOUT FLARES AND USE THEREOF 苏州艾麦锶生命科技有限公司 2024-07-25 WO claimed
US-12018299-B2 Methods and kits for quantifying adenosine-containing molecules SEVIVO LLC (US) 2024-06-25 US claimed
CN-116381072-B Biomarker for identifying sporadic gout and frequent gout and application thereof 苏州艾麦锶生命科技有限公司 2024-05-31 CN claimed
EP-0974362-A1 DRUGS CONTAINING ENZYME INHIBITORS AS THE ACTIVE INGREDIENT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2000-01-26 EP claimed
EP-0869183-A1 Genetic control of ethylene biosynthesis in plants AGRITOPE, INC. (US) 1998-10-07 EP claimed
EP-0505440-B1 GENETIC CONTROL OF ETHYLENE BIOSYNTHESIS IN PLANTS AGRITOPE INC (US) 1998-07-22 EP claimed
US-5589623-A TRANSFORMING PLANT CELLS WITH A VECTOR CONTAINING A DNA SEQUENCE ENCODING AN S-ADENOSYLMETHIONINE HYDROLASE ENZYME AGRITOPE, INC. (US) 1996-12-31 US claimed
EP-0693127-A1 USE OF TOMATO E8-DERIVED PROMOTERS TO EXPRESS HETEROLOGOUS GENES, E.G. S-ADENOSYLMETHIONINE HYDROLASE, IN RIPENING FRUIT EPITOPE, INC. (US) 1996-01-24 EP claimed
US-5416250-A Genetic control of ethylene biosynthesis in plants using S-adenosylmethionine hydrolase AGRITOPE, INC. (US) 1995-05-16 US claimed
WO-1994024294-A1 USE OF TOMATO E8-DERIVED PROMOTERS TO EXPRESS HETEROLOGOUS GENES, E.G. S-ADENOSYLMETHIONINE HYDROLASE, IN RIPENING FRUIT EPITOPE, INC. (US) 1994-10-27 WO claimed
EP-0505440-A4 GENETIC CONTROL OF ETHYLENE BIOSYNTHESIS IN PLANTS 1992-11-19 EP claimed
EP-0505440-A1 GENETIC CONTROL OF ETHYLENE BIOSYNTHESIS IN PLANTS AGRITOPE, INC. (US) 1992-09-30 EP claimed
WO-1991009112-A1 GENETIC CONTROL OF ETHYLENE BIOSYNTHESIS IN PLANTS AGRITOPE, INC. (US) 1991-06-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144829-A1 SYNBIOTIC COMPOSITION, METABOLITES, AND METHOD OF PREVENTING AND TREATING OBESITY-RELATED DISEASE MLN, COMT, MLEC AHCY 77/4885ADORA2B 3195/4885ADORA3 3598/4885
US-20260051387-A1 METABOLOMIC ANALYSIS OF PERITONEAL DIALYSIS EFFLUENT SLC43A1, SLC14A1, SLC1A5 AHCY 183/4885ADORA2B 373/4885ADORA3 1082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.