Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.55 |
| ▸ | CDK8 | P49336 | 7/20 | 0.51 |
| ▸ | CCNC | P24863 | 6/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10138248 | 0.87 | SLC22A12 (0.56) | SLC22A12CDK8CCNCCYP11B1CYP11B2 | |
| SCHEMBL578479 | 0.86 | SLC22A12 (0.55) | SLC22A12CDK8CCNCMKNK1MKNK2 | |
| SCHEMBL10138336 | 0.84 | SLC22A12 (0.54) | SLC22A12CDK8CCNCMKNK1MKNK2 | |
| SCHEMBL12114721 | 0.79 | CDK8 (0.46) | SLC22A12CDK8CCNCMKNK1MKNK2 | |
| SCHEMBL578747 | 0.78 | SLC22A12 (0.46) | SLC22A12CDK8CCNC | |
| SCHEMBL17837335 | 0.78 | PRKCZ (0.59) | SLC22A12CDK8CCNCCYP11B1CYP11B2 | |
| SCHEMBL10138319 | 0.76 | SLC22A12 (0.54) | SLC22A12CDK8CCNCMKNK1MKNK2 | |
| SCHEMBL18024134 | 0.75 | SLC22A12 (0.48) | SLC22A12CDK8CCNCCYP11B1CYP11B2 | |
| SCHEMBL28127190 | 0.75 | CYP11B1 (0.62) | SLC22A12CYP11B1CYP11B2 | |
| SCHEMBL18024287 | 0.75 | CCNC (0.51) | SLC22A12CDK8CCNCMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410273-B2 | Cyclic compound having substituted phenyl group | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-04-02 | — | — | US | disclosed |
| US-20120040936-A1 | CYCLIC COMPOUND HAVING SUBSTITUTED PHENYL GROUP | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040936-A1 | CYCLIC COMPOUND HAVING SUBSTITUTED PHENYL GROUP | BMP2, BMP4, BMP6 | SLC22A12 1300/4885CDK8 2959/4885CCNC 1592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.