Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 13/20 | 0.46 |
| ▸ | CDK8 | P49336 | 13/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL578513 | 0.88 | CCNC (0.48) | CCNCCDK8GRM2 | |
| SCHEMBL10138415 | 0.87 | CCNC (0.52) | CCNCCDK8GRM2 | |
| SCHEMBL10138499 | 0.84 | CCNC (0.43) | CCNCCDK8GRM2FFAR4 | |
| SCHEMBL578716 | 0.84 | CCNC (0.42) | CCNCCDK8GRM2FFAR4 | |
| SCHEMBL10138457 | 0.83 | CCNC (0.43) | CCNCCDK8GRM2 | |
| SCHEMBL10127743 | 0.83 | CCNC (0.43) | CCNCCDK8GRM2 | |
| Hydrochloric Acid SCHEMBL585959 | 0.82 | CCNC (0.43) | CCNCCDK8GRM2 | |
| SCHEMBL10138427 | 0.81 | CCNC (0.42) | CCNCCDK8GRM2FFAR4 | |
| SCHEMBL10138449 | 0.81 | CCNC (0.40) | CCNCCDK8GRM2FFAR4 | |
| SCHEMBL578454 | 0.81 | L3MBTL1 (0.41) | CCNCCDK8GRM2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410273-B2 | Cyclic compound having substituted phenyl group | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-04-02 | — | — | US | disclosed |
| US-8410273-B2 | Cyclic compound having substituted phenyl group | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-04-02 | — | — | US | disclosed |
| US-20120040936-A1 | CYCLIC COMPOUND HAVING SUBSTITUTED PHENYL GROUP | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
| US-20120040936-A1 | CYCLIC COMPOUND HAVING SUBSTITUTED PHENYL GROUP | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
| WO-2010116915-A1 | CYCLIC COMPOUND HAVING SUBSTITUTED PHENYL GROUP | 第一三共株式会社 (JP) | 2010-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040936-A1 | CYCLIC COMPOUND HAVING SUBSTITUTED PHENYL GROUP | BMP2, BMP4, BMP6 | CCNC 1592/4885CDK8 2959/4885GRM2 1396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.