Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12604986 | 1.00 | LMNA (0.69) | LMNAALDH1A1S1PR1S1PR3SLC6A9 | |
| SCHEMBL9614499 | 0.82 | LMNA (0.61) | LMNAALDH1A1SLC6A9KEAP1NFE2L2 | |
| SCHEMBL9614501 | 0.82 | LMNA (0.61) | LMNAALDH1A1SLC6A9KEAP1NFE2L2 | |
| SCHEMBL22408310 | 0.81 | LMNA (1.00) | LMNAALDH1A1SLC6A9KEAP1NFE2L2 | |
| SCHEMBL28166495 | 0.81 | LMNA (0.64) | LMNAALDH1A1SLC6A9KEAP1NFE2L2 | |
| Hydrochloric Acid SCHEMBL28055613 | 0.80 | LMNA (0.97) | LMNAALDH1A1SLC6A9KEAP1NFE2L2 | |
| SCHEMBL14409534 | 0.80 | LMNA (0.72) | LMNAALDH1A1SLC6A9KEAP1NFE2L2 | |
| SCHEMBL6717100 | 0.79 | ALDH1A1 (0.63) | LMNAALDH1A1S1PR3MEN1KMT2A | |
| SCHEMBL6717109 | 0.79 | ALDH1A1 (0.63) | LMNAALDH1A1S1PR3MEN1KMT2A | |
| SCHEMBL2067770 | 0.78 | LMNA (0.56) | LMNAALDH1A1SLC6A9CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43298-E1 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2012-04-03 | — | — | US | disclosed |
| US-7595299-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2009-09-29 | — | — | US | disclosed |
| US-7244721-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2007-07-17 | — | — | US | disclosed |
| US-7244721-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2007-07-17 | — | — | US | disclosed |
| US-7169760-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2007-01-30 | — | — | US | disclosed |
| US-7169760-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2007-01-30 | — | — | US | disclosed |