Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614499 | 1.00 | LMNA (0.61) | LMNACNR1CNR2SLC6A9ALDH1A1 | |
| SCHEMBL12604986 | 0.82 | LMNA (0.69) | LMNACNR1CNR2SLC6A9ALDH1A1 | |
| SCHEMBL10138758 | 0.82 | LMNA (0.69) | LMNACNR1CNR2SLC6A9ALDH1A1 | |
| SCHEMBL2067770 | 0.81 | LMNA (0.56) | LMNACNR1CNR2SLC6A9ALDH1A1 | |
| SCHEMBL28166495 | 0.79 | LMNA (0.64) | LMNACNR1CNR2SLC6A9ALDH1A1 | |
| SCHEMBL7307442 | 0.79 | CTSC (0.55) | LMNAMEN1KMT2ATSHR | |
| SCHEMBL7307439 | 0.79 | CTSC (0.55) | LMNAMEN1KMT2ATSHR | |
| SCHEMBL22408310 | 0.77 | LMNA (1.00) | LMNACNR1CNR2SLC6A9ALDH1A1 | |
| SCHEMBL28166494 | 0.77 | LMNA (0.60) | LMNACNR1CNR2SLC6A9ALDH1A1 | |
| SCHEMBL5970334 | 0.76 | MMP2 (0.49) | MMP2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431113-A4 | ATRIAL PEPTIDE DERIVATIVES | — | 1992-01-22 | — | — | EP | disclosed |
| EP-0431113-A1 | ATRIAL PEPTIDE DERIVATIVES | ABBOTT LABORATORIES (US) | 1991-06-12 | — | — | EP | disclosed |