Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL890248 | 0.83 | ALDH1A1 (0.44) | CCR4TYK2KDM4E | |
| SCHEMBL889357 | 0.81 | CCR4 (0.34) | CCR4TYK2 | |
| SCHEMBL12869429 | 0.72 | KDM4E (0.58) | KDM4E | |
| SCHEMBL12982808 | 0.69 | — | — | |
| SCHEMBL10022359 | 0.68 | KDM4E (0.50) | TYK2KDM4E | |
| SCHEMBL62767 | 0.68 | SREBF2 (0.50) | CCR4KDM4E | |
| SCHEMBL10140509 | 0.68 | FDPS (0.36) | — | |
| SCHEMBL12180285 | 0.67 | RAB9A (0.53) | KDM4E | |
| SCHEMBL12680082 | 0.66 | IDH1 (0.42) | CCR4TYK2KDM4E | |
| SCHEMBL533297 | 0.66 | CTSK (0.39) | CCR4TYK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021704-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2012-02-16 | — | — | WO | disclosed |
| WO-2011081918-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC (US) | 2011-07-07 | — | — | WO | disclosed |
| WO-2011031934-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2011-03-17 | — | — | WO | disclosed |