Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13187983 | 0.87 | FDPS (0.36) | LMNAFDPSNPC1RAB9AMEN1 | |
| SCHEMBL12841633 | 0.75 | FDPS (0.37) | LMNAFDPSNPC1RAB9AMEN1 | |
| SCHEMBL27980070 | 0.70 | FDPS (0.41) | LMNAFDPSNPC1RAB9AMEN1 | |
| SCHEMBL25647654 | 0.69 | FDPS (0.40) | LMNAFDPSNPC1RAB9AMEN1 | |
| SCHEMBL12841755 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL25222775 | 0.68 | FDPS (0.39) | LMNAFDPSNPC1RAB9AMEN1 | |
| SCHEMBL15333638 | 0.68 | FDPS (0.44) | LMNAFDPSNPC1RAB9AMEN1 | |
| SCHEMBL14853086 | 0.67 | FDPS (0.38) | LMNAFDPSNPC1RAB9AMEN1 | |
| SCHEMBL690630 | 0.67 | ITGA4 (0.43) | LMNAFDPSMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18117397 | 0.67 | FDPS (0.38) | LMNAFDPSNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021704-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2012-02-16 | — | — | WO | disclosed |
| WO-2011031934-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2011-03-17 | — | — | WO | disclosed |
| WO-2010096462-A1 | LINKED DIIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC (US) | 2010-08-26 | — | — | WO | disclosed |
| WO-2010091413-A1 | LINKED DIBENZIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. (US) | 2010-08-12 | — | — | WO | disclosed |