Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.38 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.38 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 5/20 | 0.36 |
| ▸ | LDHB | P07195 | 5/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ARG1 | P05089 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25222775 | 0.98 | FDPS (0.39) | FDPSGRIK1GRIK2GRIK3GRIK4 | |
| SCHEMBL690633 | 0.83 | GRIK1 (0.52) | FDPSGRIK1GRIK2GRIK3GRIK4 | |
| SCHEMBL690634 | 0.83 | GRIK1 (0.52) | FDPSGRIK1GRIK2GRIK3GRIK4 | |
| SCHEMBL27980070 | 0.77 | FDPS (0.41) | FDPSMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL2660958 | 0.74 | HDAC1 (0.43) | MEN1KMT2ASMN1; SMN2LDHALDHB | |
| SCHEMBL25227617 | 0.74 | KLK5 (0.43) | FDPS | |
| SCHEMBL18117397 | 0.74 | FDPS (0.38) | FDPSMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL14853086 | 0.74 | FDPS (0.38) | FDPSMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL690630 | 0.74 | ITGA4 (0.43) | FDPSGRIK1GRIK2GRIK3GRIK4 | |
| SCHEMBL690631 | 0.74 | ITGA4 (0.43) | FDPSGRIK1GRIK2GRIK3GRIK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107490-A1 | HETEROCYCLE-CONTAINING LONP1 INHIBITOR COMPOUNDS, USES AND METHODS | PRETZEL THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |