Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 2/20 | 0.47 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.47 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.47 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.47 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.47 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.47 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.47 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.47 |
| ▸ | NDUFC1 | O43677 | 1/20 | 0.47 |
| ▸ | NDUFA2 | O43678 | 1/20 | 0.47 |
| ▸ | NDUFS5 | O43920 | 1/20 | 0.47 |
| ▸ | NDUFS7 | O75251 | 1/20 | 0.47 |
| ▸ | NDUFS2 | O75306 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31618356 | 1.00 | ALOX15 (0.55) | ALOX15ALDH1A1PTGDR2HPGDHTT | |
| SCHEMBL4241452 | 0.87 | ALDH1A1 (0.61) | ALDH1A1PTGDR2HPGDHTTSMN1; SMN2 | |
| SCHEMBL25429264 | 0.86 | ALOX15 (0.52) | ALOX15TRPV1PTGESNDUFS8COXFA4 | |
| SCHEMBL24183222 | 0.85 | ALOX15 (0.61) | ALOX15TRPV1PTGESNDUFS8COXFA4 | |
| SCHEMBL8203204 | 0.81 | PTGES (0.59) | ALOX15TRPV1PTGESNDUFS8COXFA4 | |
| SCHEMBL4556002 | 0.80 | ALOX15 (0.55) | ALOX15TRPV1PTGESNDUFS8COXFA4 | |
| SCHEMBL26501138 | 0.80 | TRPV1 (0.43) | ALOX15TRPV1 | |
| SCHEMBL4556003 | 0.80 | ALOX15 (0.55) | ALOX15TRPV1PTGESNDUFS8COXFA4 | |
| SCHEMBL8215581 | 0.80 | PTGES (0.60) | ALOX15TRPV1PTGESNDUFS8COXFA4 | |
| SCHEMBL26500837 | 0.80 | KDM4E (0.44) | ALDH1A1PTGDR2HPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655344-B1 | NOVEL PHENAZINE DERIVATIVES AND THEIR USE | UNIV CATHOLIQUE LOUVAIN (BE) | 2015-11-25 | — | — | EP | disclosed |
| US-9181265-B2 | Substituted 2,3-dihydro-1H-benzo[a]pyrano[2,3-c]phenazines as anti-angiogenic and anti-cancer agents | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2015-11-10 | — | — | US | disclosed |
| US-9181265-B2 | Substituted 2,3-dihydro-1H-benzo[a]pyrano[2,3-c]phenazines as anti-angiogenic and anti-cancer agents | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2015-11-10 | — | — | US | disclosed |
| US-20130289030-A1 | NOVEL PHENAZINE DERIVATIVES AND THEIR USES | UNIVERSITE LIBRE DE BRUXELLES (BE) | 2013-10-31 | — | — | US | disclosed |
| US-20130289030-A1 | NOVEL PHENAZINE DERIVATIVES AND THEIR USES | UNIVERSITE LIBRE DE BRUXELLES (BE) | 2013-10-31 | — | — | US | disclosed |
| WO-2012085222-A1 | NOVEL PHENAZINE DERIVATIVES AND THEIR USE | UNIVERSITE CATHOLIQUE DE LOUVAIN (BE) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130289030-A1 | NOVEL PHENAZINE DERIVATIVES AND THEIR USES | VEGFA, KDR, FLT4 | ALOX15 2092/4885ALDH1A1 671/4885PTGDR2 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.