Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propionic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 6/20 | 0.33 |
| ▸ | PPARD | Q03181 | 6/20 | 0.33 |
| ▸ | PPARA | Q07869 | 6/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL28428410 | 1.00 | FFAR3 (0.67) | FFAR3TP53LDHASRRHDAC3 | |
| Propionic Acid SCHEMBL27879004 | 0.97 | FFAR3 (0.62) | FFAR3TP53LDHASRRHDAC3 | |
| Propionic Acid SCHEMBL9094207 | 0.97 | FFAR3 (0.62) | FFAR3TP53LDHASRRHDAC3 | |
| Propionic Acid SCHEMBL7115112 | 0.88 | FFAR3 (0.59) | FFAR3TP53LDHASRRHDAC3 | |
| Malonic Acid SCHEMBL5874780 | 0.87 | LDHA (0.60) | FFAR3TP53LDHASRRHDAC3 | |
| Malonic Acid SCHEMBL5874776 | 0.87 | LDHA (0.60) | FFAR3TP53LDHASRRHDAC3 | |
| Diethylamine SCHEMBL5874292 | 0.86 | TP53 (0.61) | FFAR3TP53LDHASRRHDAC3 | |
| Diethylamine SCHEMBL4340639 | 0.86 | — | — | |
| Succinic Acid SCHEMBL5874535 | 0.84 | EGLN1 (0.56) | FFAR3TP53HDAC3HDAC1HDAC2 | |
| Diethylamine SCHEMBL21145244 | 0.84 | TP53 (0.50) | FFAR3TP53LDHASRRHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11851392-B2 | Self-condensation of aldehydes | EASTMAN CHEMICAL COMPANY (US) | 2023-12-26 | — | — | US | claimed |
| EP-3880640-A1 | SELF-CONDENSATION OF ALDEHYDES | Eastman Chemical Company (US) | 2021-09-22 | — | — | EP | claimed |
| CN-112955423-A | Self-condensation of aldehydes | 伊士曼化工公司 | 2021-06-11 | — | — | CN | claimed |
| WO-2020101902-A1 | SELF-CONDENSATION OF ALDEHYDES | EASTMAN CHEMICAL COMPANY (US) | 2020-05-22 | — | — | WO | claimed |
| CN-104418825-B | The method of purification of Lipstatin | 北大方正集团有限公司 | 2016-12-28 | — | — | CN | claimed |
| CN-104418825-A | Method for purifying lipstatin | UNIV PEKING FOUNDER GROUP CO | 2015-03-18 | — | — | CN | claimed |
| CN-104292283-A | Nemadectin purification method | UNIV PEKING FOUNDER GROUP CO | 2015-01-21 | — | — | CN | claimed |
| CN-102718973-A | Method for preparation of siloxane modified thermoplastic polyester elastomer | UNIV HUBEI | 2012-10-10 | — | — | CN | claimed |
| US-20250242275-A1 | APPARATUS AND METHOD FOR PROCESSING A BIOMASS MATERIAL | BUSS-SMS-CANZLER GMBH (DE) | 2025-07-31 | — | — | US | disclosed |
| US-20250145889-A1 | METHOD FOR PROCESSING A BIOMASS MATERIAL | PROIONIC GMBH (AT) | 2025-05-08 | — | — | US | disclosed |
| WO-2025075046-A1 | ANALYSIS METHOD | 株式会社ダイセル | 2025-04-10 | — | — | WO | disclosed |
| EP-4377467-A2 | METHOD FOR PROCESSING A BIOMASS MATERIAL | proionic GmbH (AT) | 2024-06-05 | — | — | EP | disclosed |
| CN-114477249-B | Method for preparing high-purity magnesium hydroxide and calcium sulfate by adopting calcium carbide furnace purification ash | 龙岩紫云化学科技有限公司 | 2024-01-30 | — | — | CN | disclosed |
| US-11851392-B2 | Self-condensation of aldehydes | EASTMAN CHEMICAL COMPANY (US) | 2023-12-26 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| EP-0419653-A4 | DERIVATIVES OF TAXOL, PHARMACEUTICAL COMPOSITIONS THEREOF AND METHODS FOR THE PREPARATION THEREOF | — | 1991-12-04 | — | — | EP | disclosed |
| EP-0419653-A1 | DERIVATIVES OF TAXOL, PHARMACEUTICAL COMPOSITIONS THEREOF AND METHODS FOR THE PREPARATION THEREOF | THE UNIVERSITY OF KANSAS (US) | 1991-04-03 | — | — | EP | disclosed |
| US-4960790-A | ANTITUMOR AGENTS, WATER SOLUBLE | UNIVERSITY OF KANSAS (US) | 1990-10-02 | — | — | US | disclosed |
| WO-1990010443-A1 | DERIVATIVES OF TAXOL, PHARMACEUTICAL COMPOSITIONS THEREOF AND METHODS FOR THE PREPARATION THEREOF | UNIVERSITY OF KANSAS (US) | 1990-09-20 | — | — | WO | disclosed |
| US-4327039-A | Process for the production of 3-amino-1-hydroxypropane-1,1-diphosphonic acid | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1982-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11851392-B2 | Self-condensation of aldehydes | ALKBH2, DBF4, ALKBH3 | FFAR3 2825/4885TP53 2059/4885LDHA 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.