SCHEMBL463465

SCHEMBL463465

CC(C)C(=O)CCC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 5/20 0.53
LMNA P02545 4/20 0.53
ALKBH5 Q6P6C2 1/20 0.53
SUCNR1 Q9BXA5 1/20 0.53
SLC15A2 Q16348 1/20 0.48
GABRP O00591 2/20 0.46
GABRD O14764 2/20 0.46
GABRA1 P14867 2/20 0.46
GABRB1 P18505 2/20 0.46
GABRG2 P18507 2/20 0.46
GABRB3 P28472 2/20 0.46
GABRA5 P31644 2/20 0.46
GABRA3 P34903 2/20 0.46
GABRA2 P47869 2/20 0.46
GABRB2 P47870 2/20 0.46
GABRA4 P48169 2/20 0.46
GABRE P78334 2/20 0.46
GABRA6 Q16445 2/20 0.46
GABRG1 Q8N1C3 2/20 0.46
GABRG3 Q99928 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28399416 0.92 ACE (0.48) EGLN1LMNAALKBH5SUCNR1SLC15A2
SCHEMBL620412 0.87 CA1 (0.36) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL11517217 0.83 LMNA (0.58) LMNAOR51E2SLC22A6TSHRNFKB1
SCHEMBL10299251 0.83 SLC22A6 (0.58) LMNAOR51E2SLC22A6TSHRNFKB1
Succinic Acid SCHEMBL1804825 0.81 LMNA (0.60) EGLN1LMNAALKBH5SUCNR1SLC15A2
SCHEMBL22223310 0.81 TSHR (0.60) LMNAOR51E2SLC22A6TSHRNFKB1
SCHEMBL11518579 0.81 TSHR (0.60) LMNAOR51E2SLC22A6TSHRNFKB1
SCHEMBL13176551 0.81 TSHR (0.60) LMNAOR51E2SLC22A6TSHRNFKB1
SCHEMBL11518693 0.81 TSHR (0.60) LMNAOR51E2SLC22A6TSHRNFKB1
SCHEMBL27050808 0.81 TSHR (0.60) LMNAOR51E2SLC22A6TSHRNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 EP disclosed
WO-2025217212-A1 MAC1 INHIBITORS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-10-16 WO disclosed
WO-2025067111-A1 MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION 苏州必扬医药科技有限公司 2025-04-03 WO disclosed
WO-2024249888-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2024-12-05 WO disclosed
CN-118530275-A Phosphinophenyl monomer, preparation method and copolymer, preparation method and application thereof, and drilling fluid 中国石油化工股份有限公司 2024-08-23 CN disclosed
US-12043833-B2 Targeted compositions ARBUTUS BIOPHARMA CORPORATION (CA) 2024-07-23 US disclosed
US-11873288-B2 Inhibitors for soluble epoxide hydrolase (sEH) and fatty acid amide hydrolase (FAAH) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-01-16 US disclosed
US-20230355775-A1 NUCLEIC ACID, COMPOSITION AND CONJUGATE CONTAINING SAME, PREPARATION METHOD, AND USE THEREOF Suzhou Ribo Life Science Co., Ltd. (CN) 2023-11-09 US disclosed
US-20230313195-A1 NUCLEIC ACID, PHARMACEUTICAL COMPOSITION, CONJUGATE, PREPARATION METHOD, AND USE Suzhou Ribo Life Science Co., Ltd. (CN) 2023-10-05 US disclosed
CN-109956929-B Heterocyclic derivative, preparation method, pharmaceutical composition and application thereof 上海迪诺医药科技有限公司 2023-09-19 CN disclosed
US-7244721-B2 Peptides as NS3-serine protease inhibitors of hepatitis C virus SCHERING CORPORATION (US) 2007-07-17 US disclosed
US-20070117827-A1 Compositions for affecting weight loss U.S. BANK NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2007-05-24 US disclosed
US-20070032433-A1 Novel peptides as NS3-serine protease inhibitors of hepatitis C virus SCHERING CORPORATION CORVAS INTERNATIONAL, LTD. 2007-02-08 US disclosed
US-7169760-B2 Peptides as NS3-serine protease inhibitors of hepatitis C virus SCHERING CORPORATION (US) 2007-01-30 US disclosed
WO-2005097103-A2 DIABETES AND METABOLIC SYNDROME THERAPY UTILIZING CATHEPSIN B INHIBITORS AXYS PHARMACEUTICALS, INC. (US) 2005-10-20 WO disclosed
CN-1617666-A Fused heterocyclic sulfonylurea compound, herbicide containing the same, and method for controlling weeds using the same SUMITOMO CHEM TAKEDA AGRO CO (JP) 2005-05-18 CN disclosed
US-20050032650-A1 Fused heterocyclic sulfonylurea compound herbicide containing the same and method of controlling weed with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-02-10 US disclosed
EP-1466527-A1 FUSED HETEROCYCLIC SULFONYLUREA COMPOUND, HERBICIDE CONTAINING THE SAME, AND METHOD OF CONTROLLING WEED WITH THE SAME Sumitomo Chemical Takeda Agro Company, Limited (JP) 2004-10-13 EP disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070117827-A1 Compositions for affecting weight loss MC4R, MC3R, MC5R EGLN1 1048/4885LMNA 4467/4885ALKBH5 4469/4885
US-20230355775-A1 NUCLEIC ACID, COMPOSITION AND CONJUGATE CONTAINING SAME, PREPARATION METHOD, AND USE THEREOF APOB, C1QBP, APOL1 EGLN1 4649/4885LMNA 301/4885ALKBH5 821/4885
US-11873288-B2 Inhibitors for soluble epoxide hydrolase (sEH) and fatty acid amide hydrolase (FAAH) FAAH, FAAH2, EPHX2 EGLN1 244/4885LMNA 4459/4885ALKBH5 574/4885
US-20050032650-A1 Fused heterocyclic sulfonylurea compound herbicide containing the same and method of controlling weed with the same NOTUM, WEE1, DDT EGLN1 188/4885LMNA 3357/4885ALKBH5 267/4885
US-20070032433-A1 Novel peptides as NS3-serine protease inhibitors of hepatitis C virus HPN, TMPRSS15, VIP EGLN1 2552/4885LMNA 3429/4885ALKBH5 2618/4885
US-20230313195-A1 NUCLEIC ACID, PHARMACEUTICAL COMPOSITION, CONJUGATE, PREPARATION METHOD, AND USE PCSK9, PCSK7, PCSK6 EGLN1 2712/4885LMNA 56/4885ALKBH5 1110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.