Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GALR2 | O43603 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143551 | 0.80 | GALR2 (0.67) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL10143394 | 0.80 | GALR2 (0.67) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL24309298 | 0.76 | LMNA (0.56) | TP53ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL10143440 | 0.75 | KMT2A (0.54) | TP53ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL24309295 | 0.73 | TSHR (0.47) | TP53ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10143452 | 0.72 | KMT2A (0.56) | TP53ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL10143454 | 0.71 | KMT2A (0.60) | TP53ALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL10143753 | 0.70 | KDM4E (0.55) | SMN1; SMN2MAPTMEN1KMT2AGALR2 | |
| SCHEMBL23221586 | 0.70 | GALR2 (0.57) | GALR2SLC2A1 | |
| SCHEMBL24309543 | 0.70 | HPGD (0.58) | TP53ALDH1A1SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |