Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 11/20 | 0.83 |
| ▸ | GALR1 | P47211 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143794 | 0.91 | GALR2 (1.00) | GALR2GALR1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL10143549 | 0.86 | GALR2 (0.77) | GALR2GALR1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL8974362 | 0.86 | NPSR1 (0.65) | GALR2LMNANPSR1SMN1; SMN2HTT | |
| SCHEMBL11360669 | 0.80 | NPSR1 (0.57) | GALR2LMNANPSR1SMN1; SMN2HTT | |
| SCHEMBL11506640 | 0.79 | GALR2 (0.66) | GALR2GALR1LMNANPSR1MAPT | |
| SCHEMBL14503648 | 0.78 | LMNA (0.63) | GALR2LMNANPSR1SMN1; SMN2HTT | |
| SCHEMBL10144350 | 0.78 | GALR2 (0.72) | GALR2GALR1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL10143796 | 0.77 | GALR2 (1.00) | GALR2GALR1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL10143395 | 0.76 | GALR2 (0.64) | GALR2GALR1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL3245932 | 0.75 | GALR2 (0.61) | GALR2GALR1LMNANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |