Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 10/20 | 0.64 |
| ▸ | GALR1 | P47211 | 6/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144350 | 0.83 | GALR2 (0.72) | GALR2GALR1NPSR1LMNATAAR1 | |
| SCHEMBL10144177 | 0.81 | GALR2 (0.82) | GALR2GALR1TAAR1GAAKMT2A | |
| SCHEMBL11506640 | 0.81 | GALR2 (0.66) | GALR2GALR1NPSR1LMNATAAR1 | |
| SCHEMBL10143796 | 0.79 | GALR2 (1.00) | GALR2GALR1NPSR1LMNATAAR1 | |
| SCHEMBL15334687 | 0.76 | SMN1; SMN2 (0.48) | NPSR1GAAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10143794 | 0.76 | GALR2 (1.00) | GALR2GALR1NPSR1LMNATAAR1 | |
| SCHEMBL10143797 | 0.76 | GALR2 (0.83) | GALR2GALR1NPSR1LMNA | |
| SCHEMBL10143795 | 0.76 | GALR2 (0.83) | GALR2GALR1NPSR1LMNATAAR1 | |
| SCHEMBL10144353 | 0.76 | GALR2 (1.00) | GALR2GALR1NPSR1LMNATAAR1 | |
| SCHEMBL15639408 | 0.76 | ROCK2 (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |