SCHEMBL8974362

SCHEMBL8974362

Cc1ccc(Nc2nc(Nc3ccccc3)nc(N3CCCCC3)n2)c(C)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.65
LMNA P02545 4/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
KMT2A Q03164 5/20 0.62
MAPT P10636 4/20 0.62
HTT P42858 3/20 0.62
GAA P10253 1/20 0.62
TAAR1 Q96RJ0 1/20 0.62
GALR2 O43603 2/20 0.61
ALDH1A1 P00352 2/20 0.57
MEN1 O00255 3/20 0.56
ALOX15 P16050 2/20 0.56
TSHR P16473 1/20 0.56
HSD17B10 Q99714 1/20 0.56
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
GBA1 P04062 4/20 0.54
POLB P06746 2/20 0.52
TP53 P04637 1/20 0.52
MAPK1 P28482 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11360669 0.94 NPSR1 (0.57) NPSR1LMNASMN1; SMN2KMT2AMAPT
SCHEMBL14503648 0.89 LMNA (0.63) NPSR1LMNASMN1; SMN2KMT2AMAPT
SCHEMBL10143795 0.86 GALR2 (0.83) NPSR1LMNASMN1; SMN2KMT2AMAPT
SCHEMBL4544857 0.84 KCNH3 (0.53) NPSR1LMNASMN1; SMN2KMT2AMAPT
SCHEMBL11807869 0.83 NPSR1 (0.93) NPSR1LMNASMN1; SMN2KMT2AMAPT
SCHEMBL11787764 0.78 MAPT (0.63) LMNASMN1; SMN2KMT2AMAPTHTT
SCHEMBL14503144 0.78 NPSR1 (0.94) NPSR1LMNASMN1; SMN2KMT2AMAPT
SCHEMBL10143745 0.77 GALR2 (0.73) NPSR1LMNASMN1; SMN2KMT2AMAPT
SCHEMBL15613253 0.77 GAA (1.00) NPSR1LMNASMN1; SMN2KMT2AMAPT
SCHEMBL10143794 0.76 GALR2 (1.00) NPSR1LMNASMN1; SMN2KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5494718-A GLASS FIBER REINFORCED THERMOPLASTIC MATERIAL THE GEON COMPANY (US) 1996-02-27 US disclosed
EP-0587104-A2 Improved rigid smoke supressed polyvinyl chloride compounds The Geon Company (US) 1994-03-16 EP disclosed
EP-0568922-A1 Rigid thermoplastic halopolymer compounds and method for reduction of heat release THE B.F. GOODRICH COMPANY (US) 1993-11-10 EP disclosed
EP-0094604-B1 SMOKE RETARDANT VINYL HALIDE POLYMER COMPOSITIONS The B.F. GOODRICH Company (US) 1986-12-17 EP disclosed
EP-0094602-B1 SMOKE RETARDANT VINYL HALIDE POLYMER COMPOSITIONS The B.F. GOODRICH Company (US) 1986-09-17 EP disclosed
EP-0031839-B1 IMPROVED RIGID VINYL CHLORIDE POLYMER COMPOSITIONS The B.F. GOODRICH Company (US) 1985-11-13 EP disclosed
US-4507414-A COPPER OXALATE, AMINE MOLYBDATE, ALKALINE EARTH CARBONATE THE B. F. GOODRICH COMPANY (US) 1985-03-26 US disclosed
US-4464495-A FLAME RESISTANT; COPPER OXALATE; AMINE MOLYBDATE; TITANIUM DIOXIDE; VINYL CHLORIDE POLMER; ALUMINUM TRIHYDRATE; CALCIUM CARBONATE THE B. F. GOODRICH COMPANY (US) 1984-08-07 US disclosed
EP-0094604-A2 Smoke retardant vinyl halide polymer compositions The B.F. GOODRICH Company (US) 1983-11-23 EP disclosed
EP-0094602-A2 Smoke retardant vinyl halide polymer compositions The B.F. GOODRICH Company (US) 1983-11-23 EP disclosed
US-4161466-A Smoke retarded polymer compositions containing amine molybdates THE B. F. GOODRICH COMPANY (US) 1979-07-17 US disclosed
US-4153792-A SMOKE RETARDERS THE B. F. GOODRICH COMPANY (US) 1979-05-08 US disclosed
US-4129540-A MELAMINE MOLYBDATE RETARDS SMOKE AND DOESN'T DISCOLOR POLYMERS THE B. F. GOODRICH COMPANY (US) 1978-12-12 US disclosed
US-4055538-A SYNERGISTIC, A MELAMINE MOLYBDATE AND IRON OXIDE, SULFATE, ACETYLACETONATE OR HYDRATES THE B. F. GOODRICH COMPANY (US) 1977-10-25 US disclosed
US-4055537-A SYNERGISTIC MIXTURE OF A MELAMINE MOLYBDATE AND AN INORGANIC THE B. F. GOODRICH COMPANY (US) 1977-10-25 US disclosed
US-4053455-A AMINE MOLYBDATE THE B. F. GOODRICH COMPANY (US) 1977-10-11 US disclosed
US-4053454-A MELAMINE MOLYBDATE, AND NICKEL SALTS THE B. F. GOODRICH COMPANY (US) 1977-10-11 US disclosed
US-4053453-A COPPER OXALATE AND AMINE MOLYBDATE THE B. F. GOODRICH COMPANY (US) 1977-10-11 US disclosed
US-4053452-A MELAMINE MOLYBDATE AND COBALT SALTS THE B. F. GOODRICH COMPANY (US) 1977-10-11 US disclosed
US-4053451-A MELAMINE MOLYBDATE AND COPPER SALTS THE B. F. GOODRICH COMPANY (US) 1977-10-11 US disclosed