Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CDC25A | P30304 | 1/20 | 0.56 |
| ▸ | CDC25B | P30305 | 1/20 | 0.56 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.56 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11919994 | 0.79 | CYP3A4 (0.66) | ALDH1A1SMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL12311688 | 0.79 | LMNA (0.74) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL27809488 | 0.79 | TP53 (0.77) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL11996357 | 0.77 | TP53 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL6722242 | 0.76 | POLB (0.66) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL16208774 | 0.74 | POLB (0.66) | ALDH1A1SMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL6722269 | 0.73 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL5411609 | 0.73 | MEN1 (0.86) | ALDH1A1MEN1KMT2ATP53LMNA | |
| SCHEMBL5330329 | 0.73 | KMT2A (0.86) | ALDH1A1SMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL6212432 | 0.72 | LMNA (0.80) | ALDH1A1SMN1; SMN2HSD17B10TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120324421-A | Application of compound and composition thereof in preparation of drugs for treating acute kidney injury | 中国人民解放军陆军军医大学 | 2025-07-18 | — | — | CN | disclosed |
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | ALDH1A1 2125/4885SMN1; SMN2 4780/4885HSD17B10 783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.