Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | CDC25A | P30304 | 1/20 | 0.67 |
| ▸ | CDC25B | P30305 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | RGS12 | O14924 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.57 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12311688 | 0.88 | LMNA (0.74) | TP53L3MBTL1LMNACDC25ACDC25B | |
| SCHEMBL21123650 | 0.86 | TP53 (0.78) | TP53L3MBTL1LMNAALDH1A1KDM4E | |
| SCHEMBL6402656 | 0.85 | ALDH1A1 (0.72) | LMNACDC25ACDC25BALDH1A1KDM4E | |
| SCHEMBL27787551 | 0.84 | MEN1 (0.61) | TP53L3MBTL1LMNAALDH1A1KDM4E | |
| SCHEMBL27809458 | 0.84 | ALDH1A1 (0.63) | TP53L3MBTL1LMNAALDH1A1KDM4E | |
| SCHEMBL15983434 | 0.81 | ALDH1A1 (0.77) | TP53L3MBTL1LMNAALDH1A1KDM4E | |
| SCHEMBL6212432 | 0.81 | LMNA (0.80) | TP53L3MBTL1LMNACDC25ACDC25B | |
| SCHEMBL6408144 | 0.81 | HTT (0.78) | TP53L3MBTL1LMNACDC25ACDC25B | |
| SCHEMBL11996357 | 0.80 | TP53 (0.62) | TP53LMNACDC25ACDC25BALDH1A1 | |
| SCHEMBL10143969 | 0.79 | ALDH1A1 (0.70) | TP53L3MBTL1LMNACDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101805302-B | 2- (4-phenyl-3-aryloxy-1, 2, 4-triazole-5-sulfenyl) acetamide and synthesis and application thereof | UNIV NORTHWEST NORMAL | 2012-05-09 | — | — | CN | disclosed |
| CN-101805302-A | 2-(4-phenyl-3-aryloxy-1,2,4-triazole-5-sulfenyl) acetamide and synthesis and application thereof | UNIV NORTHWEST NORMAL | 2010-08-18 | — | — | CN | disclosed |