Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14707354 | 0.86 | ALDH1A1 (0.72) | ALDH1A1KMT2AKDM4EPOLBALOX12 | |
| SCHEMBL12767875 | 0.84 | NPC1 (0.62) | ALDH1A1KMT2AKDM4EPOLBALOX12 | |
| SCHEMBL12767882 | 0.81 | ALDH1A1 (0.81) | ALDH1A1KMT2AKDM4EPOLBALOX12 | |
| SCHEMBL12839911 | 0.80 | ALDH1A1 (0.61) | ALDH1A1KMT2APOLBALOX12NPC1 | |
| SCHEMBL5447995 | 0.79 | MAPT (0.68) | ALDH1A1KMT2AKDM4EPOLBALOX12 | |
| SCHEMBL7332090 | 0.77 | PYGL (0.62) | ALDH1A1KMT2AKDM4ENPC1MEN1 | |
| SCHEMBL6248871 | 0.77 | ALDH1A1 (0.88) | ALDH1A1KMT2AKDM4EALOX12NPC1 | |
| SCHEMBL4700752 | 0.76 | PYGL (0.81) | ALDH1A1KMT2APOLBNPC1MAPT | |
| SCHEMBL15966210 | 0.76 | MAPT (0.67) | ALDH1A1KMT2AKDM4EPOLBNPC1 | |
| SCHEMBL16127883 | 0.75 | PPARG (0.67) | ALDH1A1KMT2AMEN1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | ALDH1A1 2125/4885KMT2A 1652/4885KDM4E 3708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.