SCHEMBL29468637

SCHEMBL29468637

Cc1cccc(NC(=O)c2cccs2)c1C

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.72
NPC1 O15118 5/20 0.72
GAA P10253 1/20 0.62
SMN1; SMN2 Q16637 4/20 0.60
MAPT P10636 3/20 0.60
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
TP53 P04637 1/20 0.60
PKM P14618 1/20 0.60
ALDH1A1 P00352 4/20 0.60
MAPK1 P28482 1/20 0.60
APLNR P35414 1/20 0.58
GPR174 Q9BXC1 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
TSHR P16473 2/20 0.57
THRB P10828 1/20 0.57
LMNA P02545 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
KDM4E B2RXH2 1/20 0.55
HPGD P15428 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7991476 0.87 MAPT (0.68) RAB9ANPC1GAASMN1; SMN2MAPT
SCHEMBL19476108 0.82 SMN1; SMN2 (0.61) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL10144692 0.81 TSHR (0.78) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL4741225 0.81 ALDH1A1 (0.57) RAB9ANPC1GAASMN1; SMN2MAPT
SCHEMBL17712451 0.77 TSHR (0.83) RAB9ANPC1GAASMN1; SMN2MAPT
SCHEMBL12666618 0.76 MAPK1 (0.66) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL7291904 0.75 TSHR (0.74) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL28348976 0.75 MAPK1 (1.00) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL1307567 0.75 RAB9A (0.57) RAB9ANPC1MAPTMEN1KMT2A
SCHEMBL2908895 0.75 MAPT (0.62) RAB9ANPC1SMN1; SMN2MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12159098-B2 System and method for document translation in a format agnostic document viewer OPEN TEXT SA ULC (CA) 2024-12-03 US disclosed
US-20230325583-A1 SYSTEM AND METHOD FOR DOCUMENT TRANSLATION IN A FORMAT AGNOSTIC DOCUMENT VIEWER OPEN TEXT SA ULC (CA) 2023-10-12 US disclosed
US-11720743-B2 System and method for document translation in a format agnostic document viewer OPEN TEXT SA ULC (CA) 2023-08-08 US disclosed
US-20220100950-A1 SYSTEM AND METHOD FOR DOCUMENT TRANSLATION IN A FORMAT AGNOSTIC DOCUMENT VIEWER OPEN TEXT SA ULC (CA) 2022-03-31 US disclosed