Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 2/20 | 0.59 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | OGG1 | O15527 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6926037 | 0.86 | TSHR (0.55) | POLBTSHRGAASMN1; SMN2KMT2A | |
| SCHEMBL3558076 | 0.85 | SMN1; SMN2 (0.56) | AKR1C2AKR1C1TSHRGAASMN1; SMN2 | |
| SCHEMBL6922307 | 0.84 | MCHR1 (0.54) | POLBTSHRGAASMN1; SMN2KMT2A | |
| SCHEMBL8970331 | 0.83 | MAPT (0.65) | POLBGAAKMT2ANPC1RAB9A | |
| SCHEMBL5182550 | 0.79 | RAB9A (0.54) | POLBTSHRGAASMN1; SMN2KMT2A | |
| SCHEMBL12189597 | 0.78 | MAPT (0.66) | TSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6838359 | 0.77 | KMT2A (0.68) | POLBTSHRGAASMN1; SMN2KMT2A | |
| SCHEMBL7956544 | 0.77 | KMT2A (0.72) | POLBTSHRGAASMN1; SMN2KMT2A | |
| SCHEMBL12189684 | 0.77 | NR1H4 (0.65) | AKR1C2AKR1C1SMN1; SMN2KMT2ATHRB | |
| SCHEMBL38660188 | 0.76 | LMNA (0.66) | TSHRSMN1; SMN2RAB9ALMNAAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | AKR1C2 2332/4885AKR1C1 2276/4885POLB 2362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.