Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13257747 | 0.87 | KMT2A (0.79) | MAPK1KMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL11737499 | 0.86 | KMT2A (0.57) | MAPK1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL25004064 | 0.85 | KMT2A (0.54) | MAPK1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL13753854 | 0.85 | MAPK1 (0.61) | MAPK1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL23489677 | 0.85 | ROCK2 (0.62) | MAPK1KMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL13753826 | 0.82 | MAPK1 (0.76) | MAPK1KMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL13753783 | 0.82 | MAPK1 (0.76) | MAPK1KMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL13753836 | 0.82 | MAPK1 (0.76) | MAPK1KMT2ALMNAALDH1A1MEN1 | |
| Dl-Phenylalanine SCHEMBL28584723 | 0.81 | ALDH1A1 (0.53) | MAPK1KMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL11949543 | 0.80 | RAB9A (0.79) | KMT2ANPC1RAB9ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | MAPK1 3681/4885KMT2A 1652/4885NPC1 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.