Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.79 |
| ▸ | NPC1 | O15118 | 4/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | ACACB | O00763 | 1/20 | 0.63 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL880676 | 1.00 | RAB9A (0.79) | RAB9ANPC1SMN1; SMN2TP53HPGD | |
| SCHEMBL24862899 | 0.90 | RAB9A (0.67) | RAB9ANPC1SMN1; SMN2TP53HPGD | |
| SCHEMBL4103656 | 0.89 | RAB9A (0.74) | RAB9ANPC1SMN1; SMN2TP53HPGD | |
| SCHEMBL23099741 | 0.89 | NPC1 (0.74) | RAB9ANPC1SMN1; SMN2TP53HPGD | |
| SCHEMBL507202 | 0.88 | RAB9A (0.76) | RAB9ANPC1SMN1; SMN2TP53HPGD | |
| SCHEMBL17914156 | 0.86 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2TP53HPGD | |
| SCHEMBL17914162 | 0.86 | ATM (0.66) | RAB9ANPC1SMN1; SMN2TP53HPGD | |
| SCHEMBL25890576 | 0.86 | ACACB (0.67) | RAB9ANPC1SMN1; SMN2TP53HPGD | |
| SCHEMBL23099898 | 0.85 | NPC1 (0.60) | RAB9ANPC1SMN1; SMN2TP53HPGD | |
| SCHEMBL10520203 | 0.85 | CTSB (0.63) | RAB9ANPC1SMN1; SMN2TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120190820-A1 | FACILE AMIDE FORMATION VIA S-NITROSO THIOACID INTERMEDIATES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190820-A1 | FACILE AMIDE FORMATION VIA S-NITROSO THIOACID INTERMEDIATES | NAAA, TST, ASNS | RAB9A 2323/4885NPC1 4295/4885SMN1; SMN2 2383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.