Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 14/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10145489 | 0.88 | APP (0.59) | APPCYP1A2POLBSMN1; SMN2MEN1 | |
| SCHEMBL8066 | 0.85 | APP (1.00) | APPCYP1A2SNCAPOLBESR1 | |
| SCHEMBL7113427 | 0.84 | APP (0.97) | APPCYP1A2SNCAPOLBESR1 | |
| Ammonia Solution, Strong SCHEMBL29419058 | 0.84 | APP (0.97) | APPCYP1A2SNCAPOLBESR1 | |
| SCHEMBL29456578 | 0.84 | APP (0.97) | APPCYP1A2SNCAPOLBESR1 | |
| SCHEMBL1095367 | 0.84 | APP (0.97) | APPCYP1A2SNCAPOLBESR1 | |
| SCHEMBL532223 | 0.82 | APP (0.86) | APPCYP1A2SNCAPOLBESR1 | |
| Methoxymethane SCHEMBL2784008 | 0.80 | APP (0.89) | APPCYP1A2SNCAPOLBESR1 | |
| Phosphonic Acid SCHEMBL19693027 | 0.80 | APP (0.89) | APPCYP1A2SNCAPOLBESR1 | |
| Phosphoric Acid SCHEMBL307361 | 0.80 | APP (0.89) | APPCYP1A2SNCAPOLBESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114904-B2 | Luminescence quenchers and fluorogenic probes for detection of reactive species | Versitech Limited & Morningside Ventures Limited (CN) | 2012-02-14 | — | — | US | disclosed |
| US-8114904-B2 | Luminescence quenchers and fluorogenic probes for detection of reactive species | Versitech Limited & Morningside Ventures Limited (CN) | 2012-02-14 | — | — | US | disclosed |
| US-20090253118-A1 | LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES | VERSITECH LIMITED (CN) | 2009-10-08 | — | — | US | disclosed |
| US-20090253118-A1 | LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES | VERSITECH LIMITED (CN) | 2009-10-08 | — | — | US | disclosed |
| WO-2009121247-A1 | LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES | VERSITECH LIMITED (CN) | 2009-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253118-A1 | LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES | ROS1, LPO, HMOX1 | APP 4089/4885CYP1A2 1456/4885SNCA 1747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.