Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159759 | 0.80 | PSIP1 (0.46) | PSIP1 | |
| SCHEMBL8749765 | 0.77 | SMN1; SMN2 (0.36) | ALDH1A1FPR1HSD17B10PSIP1MAPT | |
| SCHEMBL21491104 | 0.76 | PSIP1 (0.32) | ALDH1A1HSD17B10PSIP1 | |
| SCHEMBL3540671 | 0.76 | PSIP1 (0.38) | ALDH1A1HSD17B10PSIP1MAPTMEN1 | |
| SCHEMBL11562313 | 0.75 | HSD11B1 (0.32) | HSD17B10PSIP1MAPT | |
| SCHEMBL2730023 | 0.75 | PTGS1 (0.32) | — | |
| SCHEMBL11565035 | 0.74 | PSIP1 (0.36) | ALDH1A1PSIP1MAPT | |
| SCHEMBL10695322 | 0.74 | F2 (0.33) | PSIP1MAPT | |
| SCHEMBL8558659 | 0.74 | ALDH1A1 (0.45) | ALDH1A1KMT2AHPGD | |
| SCHEMBL7813681 | 0.73 | CA1 (0.47) | ALDH1A1HSD17B10MAPTMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271624-A1 | IMINOPYRIDINE DERIVATIVES AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009131245-A1 | IMINOPYRIDINE DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-29 | — | — | WO | disclosed |