Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10147579 | 0.81 | NPC1 (0.33) | NPC1RAB9A | |
| SCHEMBL10146108 | 0.78 | PIK3CG (0.44) | CNR2NPC1RAB9A | |
| SCHEMBL350900 | 0.77 | PTGS2 (0.36) | CNR2 | |
| SCHEMBL13618560 | 0.74 | PIK3CG (0.35) | CNR2NPC1RAB9A | |
| SCHEMBL12245198 | 0.72 | PTGS2 (0.48) | NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL10147513 | 0.68 | CNR2 (0.35) | CNR2 | |
| SCHEMBL10147546 | 0.68 | MAPT (0.37) | CNR2 | |
| SCHEMBL26262564 | 0.66 | AOC3 (0.50) | NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL10147511 | 0.63 | MAPK14 (0.36) | — | |
| SCHEMBL352888 | 0.63 | MAOA (0.36) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418207-A1 | Sulfone compounds which modulate the CB2 receptor | Boehringer Ingelheim International GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |