Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10147512 | 0.76 | KMT2A (0.41) | LMNAPOLBKDM4ENPC1RAB9A | |
| SCHEMBL352789 | 0.72 | CNR2 (0.46) | MAPK14POLBKDM4ECNR1CNR2 | |
| SCHEMBL13475364 | 0.72 | PIK3CG (0.40) | CNR2 | |
| SCHEMBL77091 | 0.71 | LMNA (0.59) | LMNATHRBPOLBKDM4ENPC1 | |
| SCHEMBL25489131 | 0.69 | PIK3CG (0.40) | CNR2 | |
| SCHEMBL351166 | 0.67 | CNR2 (0.46) | MAPK14POLBKDM4ECNR1CNR2 | |
| SCHEMBL5340454 | 0.66 | AR (0.46) | KDM4EHAO1TRPV1FBP1 | |
| SCHEMBL78067 | 0.66 | PIK3CG (0.43) | LMNAKDM4ECNR2 | |
| SCHEMBL18468385 | 0.65 | CNR2 (0.37) | LMNAKDM4ECNR2 | |
| SCHEMBL13299827 | 0.64 | ALDH1A1 (0.50) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418207-A1 | Sulfone compounds which modulate the CB2 receptor | Boehringer Ingelheim International GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |