Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352090 | 0.77 | KMT2A (0.47) | KMT2ALMNAPOLBCASP3SENP7 | |
| SCHEMBL10147504 | 0.76 | LMNA (0.34) | LMNAPOLBKDM4ENPC1RAB9A | |
| SCHEMBL24752179 | 0.74 | POLB (0.44) | KMT2ALMNAPOLBCASP3SENP7 | |
| SCHEMBL24753886 | 0.74 | POLB (0.44) | KMT2ALMNAPOLBCASP3SENP7 | |
| SCHEMBL8252792 | 0.74 | POLB (0.46) | POLBCASP3SENP7SENP6KDM4E | |
| SCHEMBL10147515 | 0.71 | POLB (0.39) | KMT2APOLBCASP3SENP7SENP6 | |
| SCHEMBL10146061 | 0.71 | POLB (0.46) | KMT2APOLBCASP3SENP7SENP6 | |
| SCHEMBL21397907 | 0.70 | POLB (0.44) | POLBCASP3SENP7SENP6KDM4E | |
| SCHEMBL13618543 | 0.69 | POLB (0.44) | KMT2APOLBCASP3SENP7SENP6 | |
| SCHEMBL21397910 | 0.67 | POLB (0.40) | POLBCASP3SENP7SENP6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418207-A1 | Sulfone compounds which modulate the CB2 receptor | Boehringer Ingelheim International GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |