Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10147760 | 0.82 | NPC1 (0.45) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6973373 | 0.81 | ALDH1A1 (0.38) | ALDH1A1TSHRCA12CA1CA2 | |
| SCHEMBL10147750 | 0.75 | TSHR (0.33) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL19938179 | 0.71 | MAPT (0.36) | ALDH1A1MAPTTSHRCA12CA1 | |
| SCHEMBL10147765 | 0.70 | THRB (0.49) | ALDH1A1MAPTTSHRCA12CA1 | |
| SCHEMBL10147759 | 0.70 | THRB (0.49) | ALDH1A1MAPTTSHRCA12CA1 | |
| SCHEMBL10147719 | 0.70 | MAPT (0.42) | ALDH1A1MAPTTSHRCA12CA1 | |
| SCHEMBL10147748 | 0.70 | NPC1 (0.48) | ALDH1A1 | |
| SCHEMBL1626250 | 0.70 | CA2 (0.42) | ALDH1A1MAPTTSHRCA12CA1 | |
| SCHEMBL1627640 | 0.70 | CA2 (0.42) | ALDH1A1MAPTTSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097718-B2 | 3,5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof | ANADYS PHARMACEUTICALS, INC. (US) | 2012-01-17 | — | — | US | disclosed |